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Fetal origins of malignant germ cell tumours

Germ cell tumours (GCTs) are a collection of benign and malignant neoplasms derived from primordial germ cells (PGCs). They are uniquely able to generate embryonic and extraembryonic tissues, which in malignant GCTs carries prognostic and therapeutic significance. The developmental pathways underpinning GCT initiation and histogenesis are incompletely understood. Here, we studied the phylogenetic and transcriptional diversity of 15 malignant gonadal GCTs and four normal testis biopsies by sequencing 131 whole genomes and 416 transcriptomes from 14 gonadal histologies, excised by laser capture microdissection. Our findings demonstrate that tumours were initiated by whole genome duplication likely in embryogenesis, within ~5-8 cell divisions post-PGC specification, followed by chromosome 12p gains associated with invasive disease. Of note, 12p imbalances were not only generated through GCT-typical isochromosomes, but also through non-isochromosomic configurations. Whilst tumours developed along homogenous phylogenetic pathways, they spawned manifold tissues independent of genetic subclonal diversification. A key feature of GCT tissues was the expression of fetal-specific genes. The transcriptional diversity notwithstanding, we found universal transcriptional elements correlated with hallmark 12p gains. Overall, our study reveals stereotyped phylogenies and transcriptomes underpinning the development of GCT that originate in fetal life and may lend themselves to therapeutic manipulation.

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001003021 Cancer Genomics
EGAS00001003023 Cancer Genomics
EGAS00001003457 Whole Genome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00002551453 cram 5.0 GB
EGAF00002551454 cram 5.0 GB
EGAF00002551459 cram 5.1 GB
EGAF00002551460 cram 5.1 GB
EGAF00002551465 cram 5.0 GB
EGAF00002551466 cram 4.9 GB
EGAF00002551471 cram 5.0 GB
EGAF00002551472 cram 4.9 GB
EGAF00002551477 cram 5.1 GB
EGAF00002551478 cram 6.4 GB
EGAF00002551479 cram 5.3 GB
EGAF00002551483 cram 5.2 GB
EGAF00002551484 cram 6.4 GB
EGAF00002551485 cram 5.3 GB
EGAF00002551489 cram 4.8 GB
EGAF00002551495 cram 4.8 GB
EGAF00002551501 cram 4.7 GB
EGAF00002551507 cram 4.8 GB
EGAF00002551513 cram 4.8 GB
EGAF00002551519 cram 4.8 GB
EGAF00002552982 cram 5.7 GB
EGAF00002552983 cram 5.6 GB
EGAF00003441079 cram 5.2 GB
EGAF00003441080 cram 5.1 GB
EGAF00003441081 cram 5.1 GB
EGAF00003441085 cram 5.2 GB
EGAF00003441086 cram 5.0 GB
EGAF00003441087 cram 5.0 GB
EGAF00003441091 cram 5.3 GB
EGAF00003441092 cram 5.1 GB
EGAF00003441093 cram 5.1 GB
EGAF00003441097 cram 5.1 GB
EGAF00003441098 cram 4.9 GB
EGAF00003441099 cram 4.9 GB
EGAF00003441103 cram 5.2 GB
EGAF00003441104 cram 5.2 GB
EGAF00003441105 cram 5.2 GB
EGAF00003441109 cram 4.9 GB
EGAF00003441110 cram 4.8 GB
EGAF00003441111 cram 4.9 GB
EGAF00003441115 cram 5.1 GB
EGAF00003441116 cram 4.8 GB
EGAF00003441117 cram 4.8 GB
EGAF00003441120 cram 5.3 GB
EGAF00003441121 cram 5.0 GB
EGAF00003441122 cram 4.8 GB
EGAF00003441123 cram 4.8 GB
EGAF00003441126 cram 5.2 GB
EGAF00003441127 cram 5.1 GB
EGAF00003441128 cram 4.8 GB
EGAF00003441129 cram 4.7 GB
EGAF00003441132 cram 5.2 GB
EGAF00003441133 cram 5.3 GB
EGAF00003441134 cram 4.9 GB
EGAF00003441135 cram 4.8 GB
EGAF00003441167 cram 5.3 GB
EGAF00003441168 cram 5.3 GB
EGAF00003441169 cram 4.9 GB
EGAF00003441170 cram 4.8 GB
EGAF00003441173 cram 5.3 GB
EGAF00003441174 cram 5.2 GB
EGAF00003441175 cram 4.8 GB
EGAF00003441176 cram 4.8 GB
EGAF00003441179 cram 5.3 GB
EGAF00003441180 cram 4.8 GB
EGAF00003441181 cram 6.1 GB
EGAF00003441182 cram 5.0 GB
EGAF00003441186 cram 4.8 GB
EGAF00003441187 cram 6.2 GB
EGAF00003441188 cram 5.0 GB
EGAF00003441192 cram 4.8 GB
EGAF00003441193 cram 6.1 GB
EGAF00003441223 cram 5.0 GB
EGAF00003441227 cram 4.9 GB
EGAF00003441228 cram 6.1 GB
EGAF00003441229 cram 5.0 GB
EGAF00003441233 cram 6.7 GB
EGAF00003441234 cram 6.6 GB
EGAF00004040130 cram 5.5 GB
EGAF00004040131 cram 8.5 GB
EGAF00004040132 cram 9.3 GB
EGAF00004040133 cram 9.8 GB
EGAF00004040134 cram 5.3 GB
EGAF00004040135 cram 8.4 GB
EGAF00004040136 cram 9.0 GB
EGAF00004040137 cram 9.6 GB
EGAF00004040138 cram 5.5 GB
EGAF00004040139 cram 8.5 GB
EGAF00004040140 cram 9.2 GB
EGAF00004040141 cram 9.8 GB
EGAF00004040142 cram 5.5 GB
EGAF00004040143 cram 8.7 GB
EGAF00004040144 cram 9.3 GB
EGAF00004040145 cram 9.9 GB
EGAF00004185873 cram 33.5 GB
EGAF00004185874 cram 5.0 GB
EGAF00004185875 cram 4.0 GB
EGAF00004185876 cram 4.8 GB
EGAF00004185877 cram 5.1 GB
EGAF00004185878 cram 4.8 GB
EGAF00004185879 cram 4.1 GB
EGAF00004185880 cram 2.8 GB
EGAF00004185881 cram 5.0 GB
EGAF00004185882 cram 4.0 GB
EGAF00004185883 cram 4.7 GB
EGAF00004185884 cram 5.1 GB
EGAF00004185885 cram 4.8 GB
EGAF00004185886 cram 4.1 GB
EGAF00004185887 cram 2.8 GB
EGAF00004185888 cram 4.9 GB
EGAF00004185889 cram 4.0 GB
EGAF00004185890 cram 4.6 GB
EGAF00004185891 cram 4.9 GB
EGAF00004185892 cram 4.7 GB
EGAF00004185893 cram 4.0 GB
EGAF00004185894 cram 2.7 GB
EGAF00004185895 cram 4.9 GB
EGAF00004185896 cram 4.0 GB
EGAF00004185897 cram 4.7 GB
EGAF00004185898 cram 5.0 GB
EGAF00004185899 cram 4.7 GB
EGAF00004185900 cram 4.0 GB
EGAF00004185901 cram 2.8 GB
EGAF00004185902 cram 4.6 GB
EGAF00004185903 cram 4.1 GB
EGAF00004185904 cram 4.5 GB
EGAF00004185905 cram 4.8 GB
EGAF00004185906 cram 4.7 GB
EGAF00004185907 cram 4.0 GB
EGAF00004185908 cram 2.8 GB
EGAF00004855896 cram 8.3 GB
EGAF00004855899 cram 8.3 GB
EGAF00004855902 cram 8.2 GB
EGAF00004855905 cram 8.6 GB
EGAF00004921239 cram 6.8 GB
EGAF00004921240 cram 8.3 GB
EGAF00004921243 cram 7.0 GB
EGAF00004921244 cram 8.4 GB
EGAF00004921247 cram 6.8 GB
EGAF00004921248 cram 8.1 GB
EGAF00004921251 cram 7.5 GB
EGAF00004921252 cram 8.8 GB
EGAF00004921254 cram 16.7 GB
EGAF00004921256 cram 16.7 GB
EGAF00004921365 cram 10.9 GB
EGAF00004921366 cram 10.7 GB
EGAF00004921367 cram 10.7 GB
EGAF00004921371 cram 5.9 GB
EGAF00004921372 cram 5.0 GB
EGAF00004921376 cram 5.9 GB
EGAF00004921377 cram 5.0 GB
EGAF00004921381 cram 5.9 GB
EGAF00004921382 cram 5.0 GB
EGAF00004921386 cram 6.0 GB
EGAF00004921387 cram 5.1 GB
EGAF00004921391 cram 5.9 GB
EGAF00004921392 cram 5.0 GB
EGAF00004921394 cram 6.0 GB
EGAF00004921395 cram 5.4 GB
EGAF00004921396 cram 5.3 GB
EGAF00004921397 cram 5.0 GB
EGAF00004921398 cram 6.3 GB
EGAF00004921400 cram 5.9 GB
EGAF00004921401 cram 5.2 GB
EGAF00004921402 cram 5.1 GB
EGAF00004921403 cram 4.9 GB
EGAF00004921404 cram 6.2 GB
EGAF00004921406 cram 5.7 GB
EGAF00004921407 cram 5.1 GB
EGAF00004921408 cram 5.0 GB
EGAF00004921409 cram 4.8 GB
EGAF00004921410 cram 6.0 GB
EGAF00004921412 cram 5.6 GB
EGAF00004921413 cram 5.0 GB
EGAF00004921414 cram 4.9 GB
EGAF00004921415 cram 4.7 GB
EGAF00004921416 cram 5.9 GB
EGAF00004921418 cram 5.6 GB
EGAF00004921419 cram 5.0 GB
EGAF00004921420 cram 4.9 GB
EGAF00004921421 cram 4.7 GB
EGAF00004921422 cram 6.0 GB
EGAF00004921423 cram 10.3 GB
EGAF00004921426 cram 10.4 GB
EGAF00004921429 cram 10.4 GB
EGAF00004921435 cram 6.3 GB
EGAF00004921436 cram 5.3 GB
EGAF00004921440 cram 5.9 GB
EGAF00004921441 cram 4.9 GB
EGAF00004921445 cram 5.7 GB
EGAF00004921446 cram 4.8 GB
EGAF00004921450 cram 5.7 GB
EGAF00004921451 cram 4.7 GB
EGAF00004921455 cram 5.7 GB
EGAF00004921456 cram 4.8 GB
EGAF00004921460 cram 5.7 GB
EGAF00004921461 cram 4.7 GB
EGAF00004921465 cram 5.8 GB
EGAF00004921466 cram 4.8 GB
EGAF00004921468 cram 5.5 GB
EGAF00004921469 cram 5.0 GB
EGAF00004921470 cram 4.9 GB
EGAF00004921471 cram 4.7 GB
EGAF00004921472 cram 5.9 GB
EGAF00004921473 cram 7.1 GB
EGAF00004921474 cram 7.1 GB
EGAF00004921475 cram 7.1 GB
EGAF00004921476 cram 7.4 GB
EGAF00004921479 cram 6.3 GB
EGAF00004921481 cram 6.6 GB
EGAF00004921484 cram 5.9 GB
EGAF00004921486 cram 6.2 GB
EGAF00004921489 cram 5.9 GB
EGAF00004921491 cram 6.2 GB
EGAF00004921494 cram 6.0 GB
EGAF00004921496 cram 6.4 GB
EGAF00004921499 cram 6.0 GB
EGAF00004921501 cram 6.4 GB
EGAF00004921502 cram 16.8 GB
EGAF00004921504 cram 16.6 GB
EGAF00004921506 cram 4.7 GB
EGAF00004921507 cram 5.2 GB
EGAF00004921508 cram 5.0 GB
EGAF00004921509 cram 4.8 GB
EGAF00004921510 cram 5.0 GB
EGAF00004921511 cram 6.0 GB
EGAF00004921512 cram 4.8 GB
EGAF00004921514 cram 6.3 GB
EGAF00004921515 cram 5.9 GB
EGAF00004921516 cram 6.1 GB
EGAF00004921517 cram 5.6 GB
EGAF00004921518 cram 6.0 GB
EGAF00004921519 cram 5.9 GB
EGAF00004921520 cram 5.8 GB
EGAF00004921521 cram 6.3 GB
EGAF00004921522 cram 6.3 GB
EGAF00004921523 cram 6.1 GB
EGAF00004921524 cram 6.5 GB
EGAF00004921525 cram 6.5 GB
EGAF00004921526 cram 6.2 GB
EGAF00004921527 cram 5.7 GB
EGAF00004921528 cram 5.7 GB
EGAF00004921529 cram 5.7 GB
EGAF00004921530 cram 5.5 GB
EGAF00004921531 cram 5.5 GB
EGAF00004921532 cram 5.4 GB
EGAF00004921533 cram 6.1 GB
EGAF00004921534 cram 5.6 GB
EGAF00004921536 cram 5.9 GB
EGAF00004921538 cram 5.7 GB
EGAF00004921540 cram 5.9 GB
EGAF00004921542 cram 6.1 GB
EGAF00004921544 cram 6.0 GB
EGAF00004921545 cram 5.9 GB
EGAF00004921546 cram 5.8 GB
EGAF00004921547 cram 5.9 GB
EGAF00004921548 cram 5.8 GB
EGAF00004921549 cram 5.6 GB
EGAF00004921550 cram 5.5 GB
EGAF00004921551 cram 5.6 GB
EGAF00004921552 cram 5.2 GB
EGAF00004921553 cram 5.8 GB
EGAF00004921554 cram 5.9 GB
EGAF00004921555 cram 5.9 GB
EGAF00004921556 cram 5.5 GB
EGAF00004921557 cram 6.1 GB
EGAF00004921558 cram 6.1 GB
EGAF00004921559 cram 6.1 GB
EGAF00004921560 cram 5.7 GB
EGAF00004921561 cram 6.3 GB
EGAF00004921562 cram 6.2 GB
EGAF00004921563 cram 6.2 GB
EGAF00004921564 cram 5.9 GB
EGAF00004921565 cram 6.5 GB
EGAF00004921566 cram 6.0 GB
EGAF00004921567 cram 6.8 GB
EGAF00004921568 cram 5.9 GB
EGAF00004921569 cram 6.6 GB
EGAF00004921570 cram 6.2 GB
EGAF00004921571 cram 7.0 GB
EGAF00004921572 cram 6.1 GB
EGAF00004921573 cram 6.9 GB
EGAF00004921574 cram 7.2 GB
EGAF00004921575 cram 7.1 GB
EGAF00004921576 cram 6.8 GB
EGAF00004921577 cram 7.2 GB
EGAF00004921578 cram 18.5 GB
EGAF00004921580 cram 20.5 GB
EGAF00004921581 cram 22.9 GB
EGAF00004921582 cram 18.0 GB
EGAF00004921583 cram 19.7 GB
EGAF00004921584 cram 19.4 GB
EGAF00004921585 cram 19.7 GB
EGAF00004921586 cram 18.9 GB
EGAF00004921587 cram 17.1 GB
EGAF00004921588 cram 19.3 GB
EGAF00004921589 cram 21.8 GB
EGAF00004921590 cram 17.5 GB
EGAF00004921591 cram 15.2 GB
EGAF00004921592 cram 16.3 GB
EGAF00004921593 cram 15.5 GB
EGAF00004921595 cram 20.2 GB
EGAF00004921596 cram 4.5 GB
EGAF00004921598 cram 5.3 GB
EGAF00004921599 cram 6.1 GB
EGAF00004921600 cram 4.2 GB
EGAF00004921601 cram 4.9 GB
EGAF00004921602 cram 4.8 GB
EGAF00004921603 cram 5.0 GB
EGAF00004921604 cram 5.1 GB
EGAF00004921605 cram 4.3 GB
EGAF00004921606 cram 4.8 GB
EGAF00004921607 cram 5.8 GB
EGAF00004921608 cram 4.5 GB
EGAF00004921609 cram 3.9 GB
EGAF00004921610 cram 4.3 GB
EGAF00004921611 cram 3.8 GB
EGAF00004921613 cram 5.1 GB
EGAF00004921614 cram 6.7 GB
EGAF00004921615 cram 12.9 GB
EGAF00004921616 cram 14.1 GB
EGAF00004921617 cram 7.1 GB
EGAF00004921618 cram 14.0 GB
EGAF00004921619 cram 13.1 GB
EGAF00004921620 cram 12.8 GB
EGAF00004921621 cram 15.4 GB
EGAF00004921622 cram 6.2 GB
EGAF00004921623 cram 8.5 GB
EGAF00004921628 cram 6.7 GB
EGAF00004921629 cram 12.8 GB
EGAF00004921630 cram 14.0 GB
EGAF00004921631 cram 7.0 GB
EGAF00004921632 cram 13.9 GB
EGAF00004921633 cram 13.0 GB
EGAF00004921634 cram 12.7 GB
EGAF00004921635 cram 15.4 GB
EGAF00004921636 cram 6.2 GB
EGAF00004921637 cram 8.5 GB
EGAF00004921642 cram 3.7 GB
EGAF00004921643 cram 3.7 GB
EGAF00004921644 cram 3.6 GB
EGAF00004921645 cram 4.4 GB
EGAF00004921646 cram 4.3 GB
EGAF00004921647 cram 4.0 GB
EGAF00004921648 cram 4.8 GB
EGAF00004921649 cram 3.5 GB
EGAF00004921650 cram 3.3 GB
EGAF00004921651 cram 4.6 GB
EGAF00004921652 cram 6.5 GB
EGAF00004921653 cram 4.2 GB
EGAF00004921654 cram 3.6 GB
EGAF00004921655 cram 2.4 GB
EGAF00004921656 cram 4.6 GB
EGAF00004921657 cram 3.5 GB
EGAF00004921658 cram 4.4 GB
EGAF00004921659 cram 3.8 GB
EGAF00004921660 cram 3.7 GB
EGAF00004921661 cram 3.6 GB
EGAF00004921662 cram 4.4 GB
EGAF00004921663 cram 4.4 GB
EGAF00004921664 cram 4.0 GB
EGAF00004921665 cram 4.8 GB
EGAF00004921666 cram 3.5 GB
EGAF00004921667 cram 3.4 GB
EGAF00004921668 cram 4.6 GB
EGAF00004921669 cram 6.4 GB
EGAF00004921670 cram 4.2 GB
EGAF00004921671 cram 3.6 GB
EGAF00004921672 cram 2.4 GB
EGAF00004921673 cram 4.6 GB
EGAF00004921674 cram 3.5 GB
EGAF00004921675 cram 4.4 GB
EGAF00004921676 cram 3.6 GB
EGAF00004921677 cram 3.6 GB
EGAF00004921678 cram 3.5 GB
EGAF00004921679 cram 4.3 GB
EGAF00004921680 cram 4.2 GB
EGAF00004921681 cram 3.9 GB
EGAF00004921682 cram 4.7 GB
EGAF00004921683 cram 3.4 GB
EGAF00004921684 cram 3.3 GB
EGAF00004921685 cram 4.5 GB
EGAF00004921686 cram 6.4 GB
EGAF00004921687 cram 4.0 GB
EGAF00004921688 cram 3.5 GB
EGAF00004921689 cram 2.3 GB
EGAF00004921690 cram 4.6 GB
EGAF00004921691 cram 3.5 GB
EGAF00004921692 cram 4.3 GB
EGAF00004921693 cram 3.6 GB
EGAF00004921694 cram 3.6 GB
EGAF00004921695 cram 3.5 GB
EGAF00004921696 cram 4.3 GB
EGAF00004921697 cram 4.3 GB
EGAF00004921698 cram 3.9 GB
EGAF00004921699 cram 4.7 GB
EGAF00004921700 cram 3.4 GB
EGAF00004921701 cram 3.3 GB
EGAF00004921702 cram 4.5 GB
EGAF00004921703 cram 6.4 GB
EGAF00004921704 cram 4.1 GB
EGAF00004921705 cram 3.5 GB
EGAF00004921706 cram 2.4 GB
EGAF00004921707 cram 4.6 GB
EGAF00004921708 cram 3.5 GB
EGAF00004921709 cram 4.3 GB
EGAF00004921710 cram 9.6 GB
EGAF00004921711 cram 11.6 GB
EGAF00004921712 cram 11.1 GB
EGAF00004921713 cram 9.6 GB
EGAF00004921714 cram 11.6 GB
EGAF00004921715 cram 11.0 GB
EGAF00004921716 cram 9.7 GB
EGAF00004921717 cram 11.7 GB
EGAF00004921718 cram 11.1 GB
EGAF00004921723 cram 3.4 GB
EGAF00004921724 cram 3.6 GB
EGAF00004921725 cram 3.4 GB
EGAF00004921726 cram 4.2 GB
EGAF00004921727 cram 4.3 GB
EGAF00004921728 cram 3.9 GB
EGAF00004921729 cram 4.8 GB
EGAF00004921730 cram 3.3 GB
EGAF00004921731 cram 3.5 GB
EGAF00004921732 cram 4.3 GB
EGAF00004921733 cram 6.2 GB
EGAF00004921734 cram 3.9 GB
EGAF00004921735 cram 3.5 GB
EGAF00004921736 cram 2.3 GB
EGAF00004921737 cram 4.6 GB
EGAF00004921738 cram 3.5 GB
EGAF00004921739 cram 4.3 GB
EGAF00004921740 cram 7.6 GB
EGAF00004921741 cram 8.4 GB
EGAF00004921745 cram 10.5 GB
EGAF00004921746 cram 8.8 GB
EGAF00004921747 cram 7.6 GB
EGAF00004921748 cram 8.5 GB
EGAF00004921752 cram 10.5 GB
EGAF00004921753 cram 8.9 GB
EGAF00004921754 cram 7.8 GB
EGAF00004921755 cram 8.7 GB
EGAF00004921759 cram 10.7 GB
EGAF00004921760 cram 9.1 GB
EGAF00004921761 cram 9.9 GB
EGAF00004921762 cram 9.6 GB
EGAF00004921763 cram 8.4 GB
EGAF00004921764 cram 10.9 GB
EGAF00004921765 cram 10.7 GB
EGAF00004921766 cram 8.2 GB
EGAF00004921767 cram 12.4 GB
EGAF00004921768 cram 11.0 GB
EGAF00004921769 cram 8.7 GB
EGAF00004921770 cram 10.3 GB
EGAF00004921771 cram 10.6 GB
EGAF00004921772 cram 9.3 GB
EGAF00004921773 cram 9.9 GB
EGAF00004921774 cram 9.4 GB
EGAF00004921775 cram 10.2 GB
EGAF00004921776 cram 9.9 GB
EGAF00004921777 cram 8.7 GB
EGAF00004921778 cram 11.3 GB
EGAF00004921779 cram 11.0 GB
EGAF00004921780 cram 8.5 GB
EGAF00004921781 cram 12.8 GB
EGAF00004921782 cram 11.3 GB
EGAF00004921783 cram 8.9 GB
EGAF00004921784 cram 10.6 GB
EGAF00004921785 cram 10.9 GB
EGAF00004921786 cram 9.6 GB
EGAF00004921787 cram 10.2 GB
EGAF00004921788 cram 9.6 GB
EGAF00004921789 cram 10.0 GB
EGAF00004921790 cram 9.7 GB
EGAF00004921791 cram 8.5 GB
EGAF00004921792 cram 11.0 GB
EGAF00004921793 cram 10.9 GB
EGAF00004921794 cram 8.3 GB
EGAF00004921795 cram 12.5 GB
EGAF00004921796 cram 11.1 GB
EGAF00004921797 cram 8.7 GB
EGAF00004921798 cram 10.5 GB
EGAF00004921799 cram 10.7 GB
EGAF00004921800 cram 9.4 GB
EGAF00004921801 cram 10.1 GB
EGAF00004921802 cram 9.4 GB
EGAF00004921803 cram 26.4 GB
EGAF00004921804 cram 29.1 GB
EGAF00004921805 cram 23.8 GB
EGAF00004921806 cram 22.3 GB
EGAF00004921807 cram 23.2 GB
EGAF00004921808 cram 24.7 GB
EGAF00004921809 cram 23.3 GB
EGAF00004921810 cram 22.5 GB
EGAF00004921811 cram 20.4 GB
EGAF00004921812 cram 23.1 GB
EGAF00004921813 cram 23.9 GB
EGAF00004921814 cram 22.6 GB
EGAF00004921816 cram 24.7 GB
EGAF00004921817 cram 27.2 GB
EGAF00004921818 cram 23.5 GB
EGAF00004921819 cram 27.0 GB
EGAF00004921821 cram 23.1 GB
EGAF00004921822 cram 20.8 GB
EGAF00004921823 cram 22.9 GB
EGAF00004921824 cram 29.7 GB
EGAF00004921825 cram 28.4 GB
EGAF00005000635 cram 10.7 GB
EGAF00005000636 cram 10.0 GB
EGAF00005000637 cram 10.3 GB
EGAF00005000638 cram 10.7 GB
EGAF00005000639 cram 10.0 GB
EGAF00005000640 cram 10.4 GB
EGAF00005000641 cram 10.7 GB
EGAF00005000642 cram 10.0 GB
EGAF00005000643 cram 10.4 GB
EGAF00005000644 cram 33.9 GB
517 Files (3.9 TB)