Fecal WMS UC sequencing data

Fecal WMS data from NCT02749630 ulcerative colitis patients. Stool samples were collected at screening as well as on day 64 and prepared for whole metagenomic sequencing.

93 samples
DAC: EGAC00001002700
Technology: Illumina HiSeq 4000

Access Policy1 Study Files

Metadata

Request Access

NMDS DUO:0000015 (version: 2021-02-23)no general methods researchThis data use modifier indicates that use does not allow methods development research (e.g., development of software or algorithms).
TS DUO:0000025 (version: 2021-02-23)time limit on useThis data use modifier indicates that use is approved for a specific number of months.
US DUO:0000026 (version: 2021-02-23)user specific restrictionThis data use modifier indicates that use is limited to use by approved users.
PS DUO:0000027 (version: 2021-02-23)project specific restrictionThis data use modifier indicates that use is limited to use within an approved project.
IS DUO:0000028 (version: 2021-02-23)institution specific restrictionThis data use modifier indicates that use is limited to use within an approved institution.

Genentech Data Access Agreement for Academic Institutions

GENENTECH DATA ACCESS COMMITTEE DATA ACCESS AGREEMENT This Data Access Agreement (“Agreement”) between Genentech, Inc. (“Genentech”) and User andUser Institution (as defined below) governs the terms on which access will be granted to thegenotype data obtained from Genentech. In signing this Agreement, User and User Institution agree to be bound by the terms and conditions of access set out in this Agreement. For the sake of clarity, the terms of access set out in this Agreement shall govern activities conducted by the User and the User Institution (as defined below). User Institution and User are referred to within the Agreement as “You” and “Your” for convenience only. Definitions: gRED means Genentech Research and Early Development. Data means all and any human genetic data generated by gRED and requested by User through submission of an Application for Access to Genotype Data and obtained from Genentech under the terms of this Agreement. Data Subject means a person, who has been informed of the purpose for which the Data is held and has given his/her informed consent thereto. User means a researcher who has requested Data by submitting an Application for Access to Genotype Data to gRED and whose User Institution has previously completed this Data Access Agreement with respect to such Data and has received acknowledgement of its acceptance. Publications means, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. User Institution means the organization at which the User is employed, affiliated or enrolled. Genentech Data Access Committee means members of the gRED organization that are responsible for making the data access decisions for the genotype data generated by gRED. Terms and Conditions: In signing this Agreement: 1. You agree to use the Data only for the advancement of medical research. 2. You agree not to use the data for the creation of products for sale or for any commercial purpose. 3. You agree to preserve, at all times, the confidentiality of Data pertaining to Data Subjects. In particular, You undertake not to use, or attempt to use the Data to compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy.DSC: Academic Data Access Agreement vMar2021 1 4. You agree not to attempt to link the Data provided under this Agreement to any other data source on the same samples or to link the Data to any person or otherwise identify any Data Subject from the Data. 5. You agree not to transfer or disclose the Data, in whole or part, or any identifiable material derived from the Data, to others, except as necessary for data/safety monitoring or programmanagement. Should You wish to share the Data with a collaborator outside the same Institution, the third party must make a separate application for access to the Data. 6. You agree to use the Data for the approved purpose and project described in your Application for Access to Raw Exome Sequencing and/or RNA Sequencing Data; use of the Data for a new purpose or project will require a new application and approval. You agree to restrict your use of the Data to the analysis of somatic mutations and/or gene expression level only; use of these data to infer genotype is not permitted. 7. You agree that publication of Your purpose, project, and results is restricted for a one (1) year period starting from the publication date of the Genentech publication referencing the Data deposit. You will be free to publish the results of the research using the Data for the approved purpose after the one (1) year period has expired. You will not publish the Data, but will refer to the original Data deposit by Genentech and agree to acknowledge in any such publication that the research makes use of Data generated by Genentech. 8. You accept that Genentech: (a) bears no legal responsibility for the accuracy or comprehensiveness of the Data; and (b) accepts no liability for indirect, consequential, or incidental, damages or losses arising from use of the Data, or from the unavailability of, or break in access to, the Data for whatever reason. 9. You understand and acknowledge that the Data is protected by copyright and other intellectual property rights, and that duplication, except as reasonably required to carry out Your research with the Data, or sale of all or part of the Data on any media is not permitted. 10. You recognize that nothing in this Agreement shall operate to transfer to the User Institution any intellectual property rights relating to the Data. 11. You agree that You will submit a report to the Genentech Data Access Committee, if requested, on completion of the approved purpose. The Genentech Data Access Committee agrees to treat the report and all information, data, results, and conclusions contained within such report as confidential information belonging to the User Institution. 12. (a) You agree to use the Data in accordance with all applicable laws, including but not limited to applicable data privacy laws. (b)The Genentech Data Access Committee reserves the right to request and inspect data security and management documentation to ensure the adequacy of data protection measures. 13. This Agreement shall be effective as of the date of the last party to sign below (“Effective Date”) and shall terminate three (3) years after the Effective Date, unless terminated sooner pursuant to Section 14 below. Upon termination, You will be required to destroy any Data held. 14. You accept that this Agreement will terminate immediately upon any breach of this Agreement by You. Either party may terminate this Agreement upon thirty (30) days written notice for any reason. The following Sections of this Agreement shall survive its expiration or termination:DSC: Academic Data Access Agreement vMar2021 2 Sections 1 – 10, 12(a), and 14-17 15. Nothing herein shall create any association, partnership, joint venture, fiduciary duty or the relation of principal and agent between the parties hereto, it being understood that each party is acting as an independent contractor, and neither party shall have the authority to bind the other or the other’s representatives in any way. 16. Except as required by law or permitted under Section 7, neither party shall use or refer to this Agreement in the public media, or use the names or marks of the other party without express prior written permission. 17. This Agreement may be executed by the parties hereto in separate counterparts, each of which when so executed and delivered shall be deemed an original, but all such counterparts shall together constitute one and the same agreement. The parties agree that execution of this Agreement by exchanging facsimile, PDF, or e-Signature (as defined below) signatures shall have the same legal force and effect as the exchange of original signatures. Pursuant to this Agreement, e-Signatures shall mean a signature that consists of one or more letters, characters, numbers or other symbols in digital form incorporated in, attached to or associated with the electronic document, that (a) is unique to the person making the signature; (b) the technology or process used to make the signature is under the sole control of the person making the signature; (b) the technology or process can be used to identify the person using the technology or process; and (d) the electronic signature can be linked with an electronic document in such a way that it can be used to determine whether the electronic document has been changed since the electronic signature was incorporated in, attached to or associated with the electronic document. The written form shall be required to make changes to this clause as well. IN WITNESS WHEREOF, the parties have caused this Agreement to be executed by their respective duly authorized representatives as set forth below. Genentech, Inc. For and on behalf of User Institution: (Institutional or Administrative Authority) Signature: Signature: Print Name: Print Name: Title: Title: Date: Date: Read and acknowledged by User/Applicant: Signature: Print Name: Title: Date:DSC: Academic Data Access Agreement vMar2021 3

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID	Study Title	Study Type
EGAS00001006172	A Dose Escalation Study of Efmarodocokin Alfa (UTTR1147A) in Healthy Volunteers and Patients with Ulcerative Colitis	Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID	File Type	Size
EGAF00006172996	fastq.gz	59.9 MB
EGAF00006172997	fastq.gz	61.6 MB
EGAF00006172998	fastq.gz	5.4 GB
EGAF00006172999	fastq.gz	5.7 GB
EGAF00006173000	fastq.gz	13.5 GB
EGAF00006173001	fastq.gz	13.5 GB
EGAF00006173002	fastq.gz	98.6 MB
EGAF00006173003	fastq.gz	101.8 MB
EGAF00006173004	fastq.gz	2.8 MB
EGAF00006173005	fastq.gz	2.8 MB
EGAF00006173006	fastq.gz	2.8 MB
EGAF00006173007	fastq.gz	2.9 MB
EGAF00006173008	fastq.gz	18.0 GB
EGAF00006173009	fastq.gz	19.0 GB
EGAF00006173010	fastq.gz	2.8 GB
EGAF00006173011	fastq.gz	2.9 GB
EGAF00006173012	fastq.gz	580.7 MB
EGAF00006173013	fastq.gz	584.1 MB
EGAF00006173014	fastq.gz	9.5 GB
EGAF00006173015	fastq.gz	10.0 GB
EGAF00006173016	fastq.gz	460.9 MB
EGAF00006173017	fastq.gz	472.0 MB
EGAF00006173018	fastq.gz	480.2 MB
EGAF00006173019	fastq.gz	503.4 MB
EGAF00006173020	fastq.gz	7.1 GB
EGAF00006173021	fastq.gz	7.4 GB
EGAF00006173022	fastq.gz	622.0 MB
EGAF00006173023	fastq.gz	636.0 MB
EGAF00006173024	fastq.gz	284.6 MB
EGAF00006173025	fastq.gz	288.2 MB
EGAF00006173026	fastq.gz	536.1 MB
EGAF00006173027	fastq.gz	550.6 MB
EGAF00006173028	fastq.gz	6.1 GB
EGAF00006173029	fastq.gz	6.2 GB
EGAF00006173030	fastq.gz	16.5 GB
EGAF00006173031	fastq.gz	16.6 GB
EGAF00006173032	fastq.gz	6.6 GB
EGAF00006173033	fastq.gz	6.1 GB
EGAF00006173034	fastq.gz	274.1 MB
EGAF00006173035	fastq.gz	281.7 MB
EGAF00006173036	fastq.gz	6.1 GB
EGAF00006173037	fastq.gz	5.9 GB
EGAF00006173038	fastq.gz	702.8 MB
EGAF00006173039	fastq.gz	696.5 MB
EGAF00006173040	fastq.gz	703.2 MB
EGAF00006173041	fastq.gz	740.9 MB
EGAF00006173042	fastq.gz	532.5 MB
EGAF00006173043	fastq.gz	540.5 MB
EGAF00006173044	fastq.gz	348.3 MB
EGAF00006173045	fastq.gz	345.3 MB
EGAF00006173046	fastq.gz	275.0 MB
EGAF00006173047	fastq.gz	265.3 MB
EGAF00006173048	fastq.gz	528.7 MB
EGAF00006173049	fastq.gz	550.2 MB
EGAF00006173050	fastq.gz	785.6 MB
EGAF00006173051	fastq.gz	797.1 MB
EGAF00006173052	fastq.gz	459.7 MB
EGAF00006173053	fastq.gz	474.7 MB
EGAF00006173054	fastq.gz	353.6 MB
EGAF00006173055	fastq.gz	368.5 MB
EGAF00006173056	fastq.gz	4.2 GB
EGAF00006173057	fastq.gz	4.1 GB
EGAF00006173058	fastq.gz	4.2 GB
EGAF00006173059	fastq.gz	4.2 GB
EGAF00006173060	fastq.gz	429.2 MB
EGAF00006173061	fastq.gz	443.4 MB
EGAF00006173062	fastq.gz	14.0 GB
EGAF00006173063	fastq.gz	14.4 GB
EGAF00006173064	fastq.gz	649.7 MB
EGAF00006173065	fastq.gz	650.7 MB
EGAF00006173066	fastq.gz	3.5 GB
EGAF00006173067	fastq.gz	3.5 GB
EGAF00006173068	fastq.gz	26.0 GB
EGAF00006173069	fastq.gz	25.6 GB
EGAF00006173070	fastq.gz	424.2 MB
EGAF00006173071	fastq.gz	425.6 MB
EGAF00006173072	fastq.gz	8.9 GB
EGAF00006173073	fastq.gz	9.2 GB
EGAF00006173074	fastq.gz	4.8 GB
EGAF00006173075	fastq.gz	4.6 GB
EGAF00006173076	fastq.gz	609.2 MB
EGAF00006173077	fastq.gz	624.5 MB
EGAF00006173078	fastq.gz	4.7 GB
EGAF00006173079	fastq.gz	4.7 GB
EGAF00006173080	fastq.gz	6.5 GB
EGAF00006173081	fastq.gz	6.4 GB
EGAF00006173082	fastq.gz	10.2 GB
EGAF00006173083	fastq.gz	10.6 GB
EGAF00006173084	fastq.gz	632.1 MB
EGAF00006173085	fastq.gz	644.9 MB
EGAF00006173086	fastq.gz	559.1 MB
EGAF00006173087	fastq.gz	569.9 MB
EGAF00006173088	fastq.gz	521.4 MB
EGAF00006173089	fastq.gz	536.4 MB
EGAF00006173090	fastq.gz	5.3 GB
EGAF00006173091	fastq.gz	5.4 GB
EGAF00006173092	fastq.gz	4.0 GB
EGAF00006173093	fastq.gz	4.1 GB
EGAF00006173094	fastq.gz	10.9 GB
EGAF00006173095	fastq.gz	11.2 GB
EGAF00006173096	fastq.gz	17.2 GB
EGAF00006173097	fastq.gz	16.3 GB
EGAF00006173098	fastq.gz	234.7 MB
EGAF00006173099	fastq.gz	215.0 MB
EGAF00006173100	fastq.gz	3.0 MB
EGAF00006173101	fastq.gz	2.9 MB
EGAF00006173102	fastq.gz	5.4 GB
EGAF00006173103	fastq.gz	5.6 GB
EGAF00006173104	fastq.gz	5.6 GB
EGAF00006173105	fastq.gz	5.8 GB
EGAF00006173106	fastq.gz	4.9 GB
EGAF00006173107	fastq.gz	5.0 GB
EGAF00006173108	fastq.gz	8.9 GB
EGAF00006173109	fastq.gz	9.1 GB
EGAF00006173110	fastq.gz	5.7 GB
EGAF00006173111	fastq.gz	5.8 GB
EGAF00006173112	fastq.gz	591.7 MB
EGAF00006173113	fastq.gz	591.0 MB
EGAF00006173114	fastq.gz	4.6 GB
EGAF00006173115	fastq.gz	4.7 GB
EGAF00006173116	fastq.gz	475.2 MB
EGAF00006173117	fastq.gz	473.2 MB
EGAF00006173118	fastq.gz	15.3 GB
EGAF00006173119	fastq.gz	15.9 GB
EGAF00006173120	fastq.gz	642.2 MB
EGAF00006173121	fastq.gz	657.6 MB
EGAF00006173122	fastq.gz	491.7 MB
EGAF00006173123	fastq.gz	497.6 MB
EGAF00006173124	fastq.gz	502.2 MB
EGAF00006173125	fastq.gz	512.0 MB
EGAF00006173126	fastq.gz	376.5 MB
EGAF00006173127	fastq.gz	375.1 MB
EGAF00006173128	fastq.gz	406.4 MB
EGAF00006173129	fastq.gz	424.5 MB
EGAF00006173130	fastq.gz	490.4 MB
EGAF00006173131	fastq.gz	495.6 MB
EGAF00006173132	fastq.gz	5.0 GB
EGAF00006173133	fastq.gz	5.1 GB
EGAF00006173134	fastq.gz	529.3 MB
EGAF00006173135	fastq.gz	538.6 MB
EGAF00006173136	fastq.gz	4.8 GB
EGAF00006173137	fastq.gz	5.0 GB
EGAF00006173138	fastq.gz	609.4 MB
EGAF00006173139	fastq.gz	621.7 MB
EGAF00006173140	fastq.gz	3.7 GB
EGAF00006173141	fastq.gz	3.5 GB
EGAF00006173142	fastq.gz	4.7 GB
EGAF00006173143	fastq.gz	4.8 GB
EGAF00006173144	fastq.gz	4.7 GB
EGAF00006173145	fastq.gz	4.8 GB
EGAF00006173146	fastq.gz	627.6 MB
EGAF00006173147	fastq.gz	644.1 MB
EGAF00006173148	fastq.gz	475.0 MB
EGAF00006173149	fastq.gz	490.2 MB
EGAF00006173150	fastq.gz	7.2 GB
EGAF00006173151	fastq.gz	7.3 GB
EGAF00006173152	fastq.gz	158.8 MB
EGAF00006173153	fastq.gz	160.7 MB
EGAF00006173154	fastq.gz	496.4 MB
EGAF00006173155	fastq.gz	489.2 MB
EGAF00006173156	fastq.gz	4.9 GB
EGAF00006173157	fastq.gz	5.0 GB
EGAF00006173158	fastq.gz	5.2 GB
EGAF00006173159	fastq.gz	5.3 GB
EGAF00006173160	fastq.gz	6.3 GB
EGAF00006173161	fastq.gz	6.4 GB
EGAF00006173162	fastq.gz	4.7 GB
EGAF00006173163	fastq.gz	4.9 GB
EGAF00006173164	fastq.gz	4.7 GB
EGAF00006173165	fastq.gz	4.7 GB
EGAF00006173166	fastq.gz	476.7 MB
EGAF00006173167	fastq.gz	481.9 MB
EGAF00006173168	fastq.gz	222.7 MB
EGAF00006173169	fastq.gz	222.0 MB
EGAF00006173170	fastq.gz	14.3 GB
EGAF00006173171	fastq.gz	14.9 GB
EGAF00006173172	fastq.gz	529.1 MB
EGAF00006173173	fastq.gz	538.9 MB
EGAF00006173174	fastq.gz	5.6 GB
EGAF00006173175	fastq.gz	5.0 GB
EGAF00006173176	fastq.gz	685.9 MB
EGAF00006173177	fastq.gz	657.5 MB
EGAF00006173178	fastq.gz	4.8 GB
EGAF00006173179	fastq.gz	4.9 GB
EGAF00006173180	fastq.gz	170.6 MB
EGAF00006173181	fastq.gz	170.6 MB
186 Files (740.3 GB)