Mucosal 16S sequencing data

16S-V4 rRNA gene sequence data for intestinal biopsies from NCT02749630 trial participants. Biopsies from patients were collected at screening, day 30, and day 85 and prepared for 16SV4 rRNA gene sequencing.

132 samples
DAC: EGAC00001002700
Technology: Illumina MiSeq

Access Policy1 Study Files

Metadata

Request Access

NMDS DUO:0000015 (version: 2021-02-23)no general methods researchThis data use modifier indicates that use does not allow methods development research (e.g., development of software or algorithms).
TS DUO:0000025 (version: 2021-02-23)time limit on useThis data use modifier indicates that use is approved for a specific number of months.
US DUO:0000026 (version: 2021-02-23)user specific restrictionThis data use modifier indicates that use is limited to use by approved users.
PS DUO:0000027 (version: 2021-02-23)project specific restrictionThis data use modifier indicates that use is limited to use within an approved project.
IS DUO:0000028 (version: 2021-02-23)institution specific restrictionThis data use modifier indicates that use is limited to use within an approved institution.

Genentech Data Access Agreement for Academic Institutions

GENENTECH DATA ACCESS COMMITTEE DATA ACCESS AGREEMENT This Data Access Agreement (“Agreement”) between Genentech, Inc. (“Genentech”) and User andUser Institution (as defined below) governs the terms on which access will be granted to thegenotype data obtained from Genentech. In signing this Agreement, User and User Institution agree to be bound by the terms and conditions of access set out in this Agreement. For the sake of clarity, the terms of access set out in this Agreement shall govern activities conducted by the User and the User Institution (as defined below). User Institution and User are referred to within the Agreement as “You” and “Your” for convenience only. Definitions: gRED means Genentech Research and Early Development. Data means all and any human genetic data generated by gRED and requested by User through submission of an Application for Access to Genotype Data and obtained from Genentech under the terms of this Agreement. Data Subject means a person, who has been informed of the purpose for which the Data is held and has given his/her informed consent thereto. User means a researcher who has requested Data by submitting an Application for Access to Genotype Data to gRED and whose User Institution has previously completed this Data Access Agreement with respect to such Data and has received acknowledgement of its acceptance. Publications means, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. User Institution means the organization at which the User is employed, affiliated or enrolled. Genentech Data Access Committee means members of the gRED organization that are responsible for making the data access decisions for the genotype data generated by gRED. Terms and Conditions: In signing this Agreement: 1. You agree to use the Data only for the advancement of medical research. 2. You agree not to use the data for the creation of products for sale or for any commercial purpose. 3. You agree to preserve, at all times, the confidentiality of Data pertaining to Data Subjects. In particular, You undertake not to use, or attempt to use the Data to compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy.DSC: Academic Data Access Agreement vMar2021 1 4. You agree not to attempt to link the Data provided under this Agreement to any other data source on the same samples or to link the Data to any person or otherwise identify any Data Subject from the Data. 5. You agree not to transfer or disclose the Data, in whole or part, or any identifiable material derived from the Data, to others, except as necessary for data/safety monitoring or programmanagement. Should You wish to share the Data with a collaborator outside the same Institution, the third party must make a separate application for access to the Data. 6. You agree to use the Data for the approved purpose and project described in your Application for Access to Raw Exome Sequencing and/or RNA Sequencing Data; use of the Data for a new purpose or project will require a new application and approval. You agree to restrict your use of the Data to the analysis of somatic mutations and/or gene expression level only; use of these data to infer genotype is not permitted. 7. You agree that publication of Your purpose, project, and results is restricted for a one (1) year period starting from the publication date of the Genentech publication referencing the Data deposit. You will be free to publish the results of the research using the Data for the approved purpose after the one (1) year period has expired. You will not publish the Data, but will refer to the original Data deposit by Genentech and agree to acknowledge in any such publication that the research makes use of Data generated by Genentech. 8. You accept that Genentech: (a) bears no legal responsibility for the accuracy or comprehensiveness of the Data; and (b) accepts no liability for indirect, consequential, or incidental, damages or losses arising from use of the Data, or from the unavailability of, or break in access to, the Data for whatever reason. 9. You understand and acknowledge that the Data is protected by copyright and other intellectual property rights, and that duplication, except as reasonably required to carry out Your research with the Data, or sale of all or part of the Data on any media is not permitted. 10. You recognize that nothing in this Agreement shall operate to transfer to the User Institution any intellectual property rights relating to the Data. 11. You agree that You will submit a report to the Genentech Data Access Committee, if requested, on completion of the approved purpose. The Genentech Data Access Committee agrees to treat the report and all information, data, results, and conclusions contained within such report as confidential information belonging to the User Institution. 12. (a) You agree to use the Data in accordance with all applicable laws, including but not limited to applicable data privacy laws. (b)The Genentech Data Access Committee reserves the right to request and inspect data security and management documentation to ensure the adequacy of data protection measures. 13. This Agreement shall be effective as of the date of the last party to sign below (“Effective Date”) and shall terminate three (3) years after the Effective Date, unless terminated sooner pursuant to Section 14 below. Upon termination, You will be required to destroy any Data held. 14. You accept that this Agreement will terminate immediately upon any breach of this Agreement by You. Either party may terminate this Agreement upon thirty (30) days written notice for any reason. The following Sections of this Agreement shall survive its expiration or termination:DSC: Academic Data Access Agreement vMar2021 2 Sections 1 – 10, 12(a), and 14-17 15. Nothing herein shall create any association, partnership, joint venture, fiduciary duty or the relation of principal and agent between the parties hereto, it being understood that each party is acting as an independent contractor, and neither party shall have the authority to bind the other or the other’s representatives in any way. 16. Except as required by law or permitted under Section 7, neither party shall use or refer to this Agreement in the public media, or use the names or marks of the other party without express prior written permission. 17. This Agreement may be executed by the parties hereto in separate counterparts, each of which when so executed and delivered shall be deemed an original, but all such counterparts shall together constitute one and the same agreement. The parties agree that execution of this Agreement by exchanging facsimile, PDF, or e-Signature (as defined below) signatures shall have the same legal force and effect as the exchange of original signatures. Pursuant to this Agreement, e-Signatures shall mean a signature that consists of one or more letters, characters, numbers or other symbols in digital form incorporated in, attached to or associated with the electronic document, that (a) is unique to the person making the signature; (b) the technology or process used to make the signature is under the sole control of the person making the signature; (b) the technology or process can be used to identify the person using the technology or process; and (d) the electronic signature can be linked with an electronic document in such a way that it can be used to determine whether the electronic document has been changed since the electronic signature was incorporated in, attached to or associated with the electronic document. The written form shall be required to make changes to this clause as well. IN WITNESS WHEREOF, the parties have caused this Agreement to be executed by their respective duly authorized representatives as set forth below. Genentech, Inc. For and on behalf of User Institution: (Institutional or Administrative Authority) Signature: Signature: Print Name: Print Name: Title: Title: Date: Date: Read and acknowledged by User/Applicant: Signature: Print Name: Title: Date:DSC: Academic Data Access Agreement vMar2021 3

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID	Study Title	Study Type
EGAS00001006172	A Dose Escalation Study of Efmarodocokin Alfa (UTTR1147A) in Healthy Volunteers and Patients with Ulcerative Colitis	Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID	File Type	Size
EGAF00006172566	fastq.gz	83.0 kB
EGAF00006172567	fastq.gz	97.3 kB
EGAF00006172568	fastq.gz	174.3 kB
EGAF00006172569	fastq.gz	214.1 kB
EGAF00006172570	fastq.gz	95.4 kB
EGAF00006172571	fastq.gz	112.8 kB
EGAF00006172572	fastq.gz	218.8 kB
EGAF00006172573	fastq.gz	288.6 kB
EGAF00006172574	fastq.gz	282.7 kB
EGAF00006172575	fastq.gz	369.4 kB
EGAF00006172576	fastq.gz	737.1 kB
EGAF00006172577	fastq.gz	1.0 MB
EGAF00006172578	fastq.gz	4.0 MB
EGAF00006172579	fastq.gz	4.9 MB
EGAF00006172580	fastq.gz	5.2 MB
EGAF00006172581	fastq.gz	6.7 MB
EGAF00006172582	fastq.gz	4.3 MB
EGAF00006172583	fastq.gz	5.5 MB
EGAF00006172584	fastq.gz	7.0 MB
EGAF00006172585	fastq.gz	8.8 MB
EGAF00006172586	fastq.gz	4.3 MB
EGAF00006172587	fastq.gz	5.8 MB
EGAF00006172588	fastq.gz	6.2 MB
EGAF00006172589	fastq.gz	7.4 MB
EGAF00006172590	fastq.gz	5.7 MB
EGAF00006172591	fastq.gz	6.9 MB
EGAF00006172592	fastq.gz	5.7 MB
EGAF00006172593	fastq.gz	6.7 MB
EGAF00006172594	fastq.gz	1.5 MB
EGAF00006172595	fastq.gz	1.8 MB
EGAF00006172596	fastq.gz	5.3 MB
EGAF00006172597	fastq.gz	6.4 MB
EGAF00006172598	fastq.gz	3.7 MB
EGAF00006172599	fastq.gz	4.8 MB
EGAF00006172600	fastq.gz	7.4 MB
EGAF00006172601	fastq.gz	9.3 MB
EGAF00006172602	fastq.gz	6.0 MB
EGAF00006172603	fastq.gz	7.5 MB
EGAF00006172604	fastq.gz	6.1 MB
EGAF00006172605	fastq.gz	8.6 MB
EGAF00006172606	fastq.gz	3.3 MB
EGAF00006172607	fastq.gz	4.0 MB
EGAF00006172608	fastq.gz	5.9 MB
EGAF00006172609	fastq.gz	7.2 MB
EGAF00006172610	fastq.gz	1.8 MB
EGAF00006172611	fastq.gz	2.6 MB
EGAF00006172612	fastq.gz	10.4 MB
EGAF00006172613	fastq.gz	12.6 MB
EGAF00006172614	fastq.gz	4.2 MB
EGAF00006172615	fastq.gz	5.1 MB
EGAF00006172616	fastq.gz	4.6 MB
EGAF00006172617	fastq.gz	5.8 MB
EGAF00006172618	fastq.gz	3.9 MB
EGAF00006172619	fastq.gz	4.9 MB
EGAF00006172620	fastq.gz	7.3 MB
EGAF00006172621	fastq.gz	8.8 MB
EGAF00006172622	fastq.gz	8.0 MB
EGAF00006172623	fastq.gz	9.7 MB
EGAF00006172624	fastq.gz	514.6 kB
EGAF00006172625	fastq.gz	644.4 kB
EGAF00006172626	fastq.gz	7.0 MB
EGAF00006172627	fastq.gz	8.9 MB
EGAF00006172628	fastq.gz	5.8 MB
EGAF00006172629	fastq.gz	6.9 MB
EGAF00006172630	fastq.gz	7.4 MB
EGAF00006172631	fastq.gz	9.0 MB
EGAF00006172632	fastq.gz	8.1 MB
EGAF00006172633	fastq.gz	9.8 MB
EGAF00006172634	fastq.gz	8.5 MB
EGAF00006172635	fastq.gz	10.9 MB
EGAF00006172636	fastq.gz	86.6 kB
EGAF00006172637	fastq.gz	107.6 kB
EGAF00006172638	fastq.gz	6.3 MB
EGAF00006172639	fastq.gz	8.4 MB
EGAF00006172640	fastq.gz	2.2 MB
EGAF00006172641	fastq.gz	2.8 MB
EGAF00006172642	fastq.gz	5.6 MB
EGAF00006172643	fastq.gz	6.8 MB
EGAF00006172644	fastq.gz	5.0 MB
EGAF00006172645	fastq.gz	5.8 MB
EGAF00006172646	fastq.gz	6.5 MB
EGAF00006172647	fastq.gz	8.0 MB
EGAF00006172648	fastq.gz	1.8 MB
EGAF00006172649	fastq.gz	2.5 MB
EGAF00006172650	fastq.gz	6.0 MB
EGAF00006172651	fastq.gz	7.6 MB
EGAF00006172652	fastq.gz	39.6 MB
EGAF00006172653	fastq.gz	49.0 MB
EGAF00006172654	fastq.gz	4.5 MB
EGAF00006172655	fastq.gz	5.7 MB
EGAF00006172656	fastq.gz	5.6 MB
EGAF00006172657	fastq.gz	8.9 MB
EGAF00006172658	fastq.gz	10.8 MB
EGAF00006172659	fastq.gz	16.5 MB
EGAF00006172660	fastq.gz	1.4 MB
EGAF00006172661	fastq.gz	1.8 MB
EGAF00006172662	fastq.gz	9.9 MB
EGAF00006172663	fastq.gz	13.0 MB
EGAF00006172664	fastq.gz	6.1 MB
EGAF00006172665	fastq.gz	7.7 MB
EGAF00006172666	fastq.gz	2.2 MB
EGAF00006172667	fastq.gz	3.2 MB
EGAF00006172668	fastq.gz	8.4 MB
EGAF00006172669	fastq.gz	10.1 MB
EGAF00006172670	fastq.gz	5.0 MB
EGAF00006172671	fastq.gz	6.4 MB
EGAF00006172672	fastq.gz	6.8 MB
EGAF00006172673	fastq.gz	8.5 MB
EGAF00006172674	fastq.gz	5.2 MB
EGAF00006172675	fastq.gz	6.6 MB
EGAF00006172676	fastq.gz	5.3 MB
EGAF00006172677	fastq.gz	7.0 MB
EGAF00006172678	fastq.gz	6.8 MB
EGAF00006172679	fastq.gz	8.5 MB
EGAF00006172680	fastq.gz	4.1 MB
EGAF00006172681	fastq.gz	5.4 MB
EGAF00006172682	fastq.gz	35.4 kB
EGAF00006172683	fastq.gz	44.0 kB
EGAF00006172684	fastq.gz	7.9 MB
EGAF00006172685	fastq.gz	9.7 MB
EGAF00006172686	fastq.gz	1.1 MB
EGAF00006172687	fastq.gz	1.4 MB
EGAF00006172688	fastq.gz	5.0 MB
EGAF00006172689	fastq.gz	6.2 MB
EGAF00006172690	fastq.gz	3.7 MB
EGAF00006172691	fastq.gz	4.4 MB
EGAF00006172692	fastq.gz	5.9 MB
EGAF00006172693	fastq.gz	7.5 MB
EGAF00006172694	fastq.gz	7.5 MB
EGAF00006172695	fastq.gz	9.4 MB
EGAF00006172696	fastq.gz	6.4 MB
EGAF00006172697	fastq.gz	8.5 MB
EGAF00006172698	fastq.gz	4.3 MB
EGAF00006172699	fastq.gz	5.3 MB
EGAF00006172700	fastq.gz	8.4 MB
EGAF00006172701	fastq.gz	10.6 MB
EGAF00006172702	fastq.gz	7.0 MB
EGAF00006172703	fastq.gz	8.7 MB
EGAF00006172704	fastq.gz	2.3 MB
EGAF00006172705	fastq.gz	3.0 MB
EGAF00006172706	fastq.gz	6.1 MB
EGAF00006172707	fastq.gz	7.8 MB
EGAF00006172708	fastq.gz	11.9 MB
EGAF00006172709	fastq.gz	15.6 MB
EGAF00006172710	fastq.gz	8.3 MB
EGAF00006172711	fastq.gz	12.5 MB
EGAF00006172712	fastq.gz	6.9 MB
EGAF00006172713	fastq.gz	8.4 MB
EGAF00006172714	fastq.gz	6.3 MB
EGAF00006172715	fastq.gz	8.2 MB
EGAF00006172716	fastq.gz	5.4 MB
EGAF00006172717	fastq.gz	6.8 MB
EGAF00006172718	fastq.gz	9.8 MB
EGAF00006172719	fastq.gz	12.0 MB
EGAF00006172720	fastq.gz	6.8 MB
EGAF00006172721	fastq.gz	8.6 MB
EGAF00006172722	fastq.gz	6.3 MB
EGAF00006172723	fastq.gz	7.8 MB
EGAF00006172724	fastq.gz	4.7 MB
EGAF00006172725	fastq.gz	5.8 MB
EGAF00006172726	fastq.gz	5.4 MB
EGAF00006172727	fastq.gz	7.3 MB
EGAF00006172728	fastq.gz	5.2 MB
EGAF00006172729	fastq.gz	6.7 MB
EGAF00006172730	fastq.gz	5.8 MB
EGAF00006172731	fastq.gz	7.3 MB
EGAF00006172732	fastq.gz	5.4 MB
EGAF00006172733	fastq.gz	7.0 MB
EGAF00006172734	fastq.gz	1.6 MB
EGAF00006172735	fastq.gz	2.2 MB
EGAF00006172736	fastq.gz	4.8 MB
EGAF00006172737	fastq.gz	6.1 MB
EGAF00006172738	fastq.gz	7.9 MB
EGAF00006172739	fastq.gz	10.5 MB
EGAF00006172740	fastq.gz	7.2 MB
EGAF00006172741	fastq.gz	9.1 MB
EGAF00006172742	fastq.gz	6.8 MB
EGAF00006172743	fastq.gz	8.8 MB
EGAF00006172744	fastq.gz	51.0 MB
EGAF00006172745	fastq.gz	62.8 MB
EGAF00006172746	fastq.gz	3.8 MB
EGAF00006172747	fastq.gz	4.8 MB
EGAF00006172748	fastq.gz	8.2 MB
EGAF00006172749	fastq.gz	10.1 MB
EGAF00006172750	fastq.gz	1.3 MB
EGAF00006172751	fastq.gz	1.7 MB
EGAF00006172752	fastq.gz	74.1 MB
EGAF00006172753	fastq.gz	91.6 MB
EGAF00006172754	fastq.gz	6.3 MB
EGAF00006172755	fastq.gz	7.9 MB
EGAF00006172756	fastq.gz	4.1 MB
EGAF00006172757	fastq.gz	5.6 MB
EGAF00006172758	fastq.gz	7.6 MB
EGAF00006172759	fastq.gz	9.5 MB
EGAF00006172760	fastq.gz	8.2 MB
EGAF00006172761	fastq.gz	10.4 MB
EGAF00006172762	fastq.gz	4.4 MB
EGAF00006172763	fastq.gz	5.6 MB
EGAF00006172764	fastq.gz	6.3 MB
EGAF00006172765	fastq.gz	7.7 MB
EGAF00006172766	fastq.gz	108.6 MB
EGAF00006172767	fastq.gz	135.9 MB
EGAF00006172768	fastq.gz	5.2 MB
EGAF00006172769	fastq.gz	6.3 MB
EGAF00006172770	fastq.gz	6.3 MB
EGAF00006172771	fastq.gz	8.4 MB
EGAF00006172772	fastq.gz	1.1 MB
EGAF00006172773	fastq.gz	1.4 MB
EGAF00006172774	fastq.gz	5.3 MB
EGAF00006172775	fastq.gz	6.7 MB
EGAF00006172776	fastq.gz	4.7 MB
EGAF00006172777	fastq.gz	5.9 MB
EGAF00006172778	fastq.gz	69.8 MB
EGAF00006172779	fastq.gz	85.4 MB
EGAF00006172780	fastq.gz	7.9 MB
EGAF00006172781	fastq.gz	10.3 MB
EGAF00006172782	fastq.gz	5.3 MB
EGAF00006172783	fastq.gz	6.5 MB
EGAF00006172784	fastq.gz	7.1 MB
EGAF00006172785	fastq.gz	8.5 MB
EGAF00006172786	fastq.gz	6.8 MB
EGAF00006172787	fastq.gz	8.3 MB
EGAF00006172788	fastq.gz	6.3 MB
EGAF00006172789	fastq.gz	7.6 MB
EGAF00006172790	fastq.gz	120.2 MB
EGAF00006172791	fastq.gz	157.6 MB
EGAF00006172792	fastq.gz	4.8 MB
EGAF00006172793	fastq.gz	6.2 MB
EGAF00006172794	fastq.gz	7.1 MB
EGAF00006172795	fastq.gz	8.5 MB
EGAF00006172796	fastq.gz	6.0 MB
EGAF00006172797	fastq.gz	7.6 MB
EGAF00006172798	fastq.gz	12.2 MB
EGAF00006172799	fastq.gz	15.7 MB
EGAF00006172800	fastq.gz	6.1 MB
EGAF00006172801	fastq.gz	7.8 MB
EGAF00006172802	fastq.gz	2.7 MB
EGAF00006172803	fastq.gz	3.5 MB
EGAF00006172804	fastq.gz	4.2 MB
EGAF00006172805	fastq.gz	5.8 MB
EGAF00006172806	fastq.gz	6.6 MB
EGAF00006172807	fastq.gz	8.6 MB
EGAF00006172808	fastq.gz	7.1 MB
EGAF00006172809	fastq.gz	9.1 MB
EGAF00006172810	fastq.gz	439.4 kB
EGAF00006172811	fastq.gz	553.4 kB
EGAF00006172812	fastq.gz	6.1 MB
EGAF00006172813	fastq.gz	7.8 MB
EGAF00006172814	fastq.gz	4.5 MB
EGAF00006172815	fastq.gz	5.6 MB
EGAF00006172816	fastq.gz	8.0 MB
EGAF00006172817	fastq.gz	10.7 MB
EGAF00006172818	fastq.gz	4.9 MB
EGAF00006172819	fastq.gz	6.3 MB
EGAF00006172820	fastq.gz	6.9 MB
EGAF00006172821	fastq.gz	8.7 MB
EGAF00006172822	fastq.gz	4.8 MB
EGAF00006172823	fastq.gz	6.1 MB
EGAF00006172824	fastq.gz	6.9 MB
EGAF00006172825	fastq.gz	8.8 MB
EGAF00006172826	fastq.gz	4.4 MB
EGAF00006172827	fastq.gz	5.4 MB
EGAF00006172828	fastq.gz	1.7 MB
EGAF00006172829	fastq.gz	2.5 MB
264 Files (2.6 GB)