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MESA colorectal cancer cfDNA EM-seq dataset

This dataset contains the methylation sequencing data of 60 nonCancer and 70 colorectal cancer cfDNA samples. The methylation library is constructed by using NEBNext Enzymatic-seq Kit.

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MESA data access policy

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets generated by Dr. David J. Taggart (details of which are set out in Appendix I) at Helio Genomics, Irvine, CA 92618, USA. In signing this agreement the User Institution agrees to be bound by these terms and conditions. Definitions Authorized Personnel: The individuals at the User Institution to whom Helio Genomics grants access to the Data. This includes the User, the individuals listed in Appendix II. Details of the initial Authorized Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: Dr David Taggart and the collaborators listed in Appendix I are responsible for the development, organization, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data: <please insert>   1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorized Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognizing the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analyzing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries, only with written permission from Helio Genomics. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf) in conformity with the Organization for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify the Data Producers within 30 days of any changes or departures of Authorized Personnel. 13. The User Institution will notify the Data Producers prior to any significant changes to the protocol for the Project. 14. The User Institution will notify the Data Producers as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. Helio Genomics may terminate this agreement by written notice to the User Institution at any time. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorized Personnel. The User Institution will ensure that the Authorized Personnel comply with the terms of this agreement. 19. The User Institution warrants that it has obtained approval by the local institutional review board/research ethics committee (IRB/REC) before the Project commences. 20. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of England and Wales and shall be subject to the exclusive jurisdiction of the English courts.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001006462 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00006623497 fastq.gz 356.2 MB
EGAF00006623498 fastq.gz 513.3 MB
EGAF00006623499 fastq.gz 382.1 MB
EGAF00006623500 fastq.gz 553.7 MB
EGAF00006623501 fastq.gz 319.0 MB
EGAF00006623502 fastq.gz 458.1 MB
EGAF00006623503 fastq.gz 401.4 MB
EGAF00006623504 fastq.gz 585.1 MB
EGAF00006623505 fastq.gz 422.4 MB
EGAF00006623506 fastq.gz 611.4 MB
EGAF00006623507 fastq.gz 354.8 MB
EGAF00006623508 fastq.gz 510.4 MB
EGAF00006623509 fastq.gz 276.9 MB
EGAF00006623510 fastq.gz 400.7 MB
EGAF00006623511 fastq.gz 333.8 MB
EGAF00006623512 fastq.gz 485.8 MB
EGAF00006623513 fastq.gz 339.0 MB
EGAF00006623514 fastq.gz 478.7 MB
EGAF00006623515 fastq.gz 272.0 MB
EGAF00006623516 fastq.gz 391.6 MB
EGAF00006623523 fastq.gz 366.7 MB
EGAF00006623525 fastq.gz 315.0 MB
EGAF00006623526 fastq.gz 452.2 MB
EGAF00006623527 fastq.gz 217.1 MB
EGAF00006623528 fastq.gz 306.9 MB
EGAF00006623529 fastq.gz 334.7 MB
EGAF00006623530 fastq.gz 490.4 MB
EGAF00006623531 fastq.gz 319.0 MB
EGAF00006623532 fastq.gz 467.5 MB
EGAF00006623533 fastq.gz 309.5 MB
EGAF00006623534 fastq.gz 452.3 MB
EGAF00006623535 fastq.gz 378.7 MB
EGAF00006623536 fastq.gz 545.3 MB
EGAF00006623537 fastq.gz 324.6 MB
EGAF00006623538 fastq.gz 463.5 MB
EGAF00006623539 fastq.gz 246.8 MB
EGAF00006623540 fastq.gz 361.4 MB
EGAF00006623541 fastq.gz 213.5 MB
EGAF00006623542 fastq.gz 307.9 MB
EGAF00006623543 fastq.gz 309.0 MB
EGAF00006623544 fastq.gz 452.3 MB
EGAF00006623545 fastq.gz 283.7 MB
EGAF00006623546 fastq.gz 409.6 MB
EGAF00006623547 fastq.gz 288.4 MB
EGAF00006623548 fastq.gz 413.4 MB
EGAF00006623549 fastq.gz 292.1 MB
EGAF00006623550 fastq.gz 429.6 MB
EGAF00006623551 fastq.gz 209.3 MB
EGAF00006623552 fastq.gz 299.5 MB
EGAF00006623553 fastq.gz 281.5 MB
EGAF00006623554 fastq.gz 407.6 MB
EGAF00006623555 fastq.gz 274.0 MB
EGAF00006623556 fastq.gz 401.1 MB
EGAF00006623557 fastq.gz 329.4 MB
EGAF00006623558 fastq.gz 489.3 MB
EGAF00006623559 fastq.gz 283.9 MB
EGAF00006623560 fastq.gz 418.8 MB
EGAF00006623561 fastq.gz 254.7 MB
EGAF00006623562 fastq.gz 368.5 MB
EGAF00006623563 fastq.gz 268.1 MB
EGAF00006623564 fastq.gz 386.8 MB
EGAF00006623565 fastq.gz 208.8 MB
EGAF00006623566 fastq.gz 298.9 MB
EGAF00006623567 fastq.gz 298.5 MB
EGAF00006623568 fastq.gz 431.4 MB
EGAF00006623569 fastq.gz 362.0 MB
EGAF00006623570 fastq.gz 517.8 MB
EGAF00006623571 fastq.gz 286.1 MB
EGAF00006623572 fastq.gz 414.8 MB
EGAF00006623573 fastq.gz 264.0 MB
EGAF00006623574 fastq.gz 385.3 MB
EGAF00006623575 fastq.gz 350.2 MB
EGAF00006623576 fastq.gz 509.5 MB
EGAF00006623577 fastq.gz 210.1 MB
EGAF00006623578 fastq.gz 299.5 MB
EGAF00006623579 fastq.gz 326.3 MB
EGAF00006623580 fastq.gz 466.7 MB
EGAF00006623581 fastq.gz 331.8 MB
EGAF00006623582 fastq.gz 475.3 MB
EGAF00006623583 fastq.gz 256.6 MB
EGAF00006623584 fastq.gz 372.1 MB
EGAF00006623585 fastq.gz 249.5 MB
EGAF00006623586 fastq.gz 358.7 MB
EGAF00006623587 fastq.gz 233.1 MB
EGAF00006623588 fastq.gz 335.8 MB
EGAF00006623589 fastq.gz 273.9 MB
EGAF00006623590 fastq.gz 391.5 MB
EGAF00006623591 fastq.gz 273.5 MB
EGAF00006623592 fastq.gz 406.5 MB
EGAF00006623593 fastq.gz 355.1 MB
EGAF00006623594 fastq.gz 518.3 MB
EGAF00006623595 fastq.gz 270.3 MB
EGAF00006623596 fastq.gz 396.3 MB
EGAF00006623597 fastq.gz 255.8 MB
EGAF00006623598 fastq.gz 363.1 MB
EGAF00006623599 fastq.gz 257.2 MB
EGAF00006623600 fastq.gz 369.0 MB
EGAF00006623601 fastq.gz 293.4 MB
EGAF00006623602 fastq.gz 426.5 MB
EGAF00006623603 fastq.gz 245.8 MB
EGAF00006623604 fastq.gz 355.8 MB
EGAF00006623605 fastq.gz 281.0 MB
EGAF00006623606 fastq.gz 408.9 MB
EGAF00006623607 fastq.gz 252.6 MB
EGAF00006623608 fastq.gz 369.7 MB
EGAF00006623609 fastq.gz 145.6 MB
EGAF00006623610 fastq.gz 205.3 MB
EGAF00006623611 fastq.gz 142.6 MB
EGAF00006623612 fastq.gz 200.0 MB
EGAF00006623613 fastq.gz 165.5 MB
EGAF00006623614 fastq.gz 234.5 MB
EGAF00006623615 fastq.gz 178.9 MB
EGAF00006623616 fastq.gz 252.9 MB
EGAF00006623617 fastq.gz 191.6 MB
EGAF00006623618 fastq.gz 272.3 MB
EGAF00006623619 fastq.gz 209.9 MB
EGAF00006623620 fastq.gz 301.0 MB
EGAF00006623621 fastq.gz 184.4 MB
EGAF00006623622 fastq.gz 259.1 MB
EGAF00006623623 fastq.gz 206.7 MB
EGAF00006623624 fastq.gz 291.6 MB
EGAF00006623625 fastq.gz 237.0 MB
EGAF00006623626 fastq.gz 334.3 MB
EGAF00006623627 fastq.gz 215.6 MB
EGAF00006623628 fastq.gz 303.7 MB
EGAF00006623629 fastq.gz 190.5 MB
EGAF00006623630 fastq.gz 271.8 MB
EGAF00006623631 fastq.gz 225.6 MB
EGAF00006623632 fastq.gz 317.6 MB
EGAF00006623633 fastq.gz 218.6 MB
EGAF00006623634 fastq.gz 305.9 MB
EGAF00006623635 fastq.gz 174.8 MB
EGAF00006623636 fastq.gz 244.3 MB
EGAF00006623637 fastq.gz 169.9 MB
EGAF00006623638 fastq.gz 237.4 MB
EGAF00006623639 fastq.gz 245.5 MB
EGAF00006623640 fastq.gz 336.0 MB
EGAF00006623641 fastq.gz 180.1 MB
EGAF00006623642 fastq.gz 254.5 MB
EGAF00006623643 fastq.gz 144.5 MB
EGAF00006623644 fastq.gz 200.9 MB
EGAF00006623645 fastq.gz 244.9 MB
EGAF00006623646 fastq.gz 349.4 MB
EGAF00006623647 fastq.gz 274.9 MB
EGAF00006623648 fastq.gz 383.9 MB
EGAF00006623649 fastq.gz 238.1 MB
EGAF00006623650 fastq.gz 330.2 MB
EGAF00006623651 fastq.gz 216.5 MB
EGAF00006623652 fastq.gz 308.3 MB
EGAF00006623653 fastq.gz 174.3 MB
EGAF00006623654 fastq.gz 246.7 MB
EGAF00006623655 fastq.gz 167.8 MB
EGAF00006623656 fastq.gz 236.8 MB
EGAF00006623657 fastq.gz 228.1 MB
EGAF00006623658 fastq.gz 326.3 MB
EGAF00006623659 fastq.gz 210.9 MB
EGAF00006623660 fastq.gz 304.0 MB
EGAF00006623661 fastq.gz 226.3 MB
EGAF00006623662 fastq.gz 319.8 MB
EGAF00006623663 fastq.gz 225.9 MB
EGAF00006623664 fastq.gz 314.7 MB
EGAF00006623665 fastq.gz 263.0 MB
EGAF00006623666 fastq.gz 381.0 MB
EGAF00006623667 fastq.gz 167.0 MB
EGAF00006623668 fastq.gz 238.3 MB
EGAF00006623669 fastq.gz 206.1 MB
EGAF00006623670 fastq.gz 292.0 MB
EGAF00006623671 fastq.gz 236.4 MB
EGAF00006623672 fastq.gz 336.1 MB
EGAF00006623673 fastq.gz 209.6 MB
EGAF00006623674 fastq.gz 294.9 MB
EGAF00006623675 fastq.gz 292.4 MB
EGAF00006623676 fastq.gz 412.9 MB
EGAF00006623677 fastq.gz 358.3 MB
EGAF00006623678 fastq.gz 520.9 MB
EGAF00006623679 fastq.gz 221.0 MB
EGAF00006623680 fastq.gz 308.4 MB
EGAF00006623681 fastq.gz 190.3 MB
EGAF00006623682 fastq.gz 269.4 MB
EGAF00006623683 fastq.gz 204.8 MB
EGAF00006623684 fastq.gz 291.8 MB
EGAF00006623685 fastq.gz 199.3 MB
EGAF00006623686 fastq.gz 280.5 MB
EGAF00006623687 fastq.gz 159.1 MB
EGAF00006623688 fastq.gz 223.8 MB
EGAF00006623689 fastq.gz 157.0 MB
EGAF00006623690 fastq.gz 219.9 MB
EGAF00006623691 fastq.gz 222.4 MB
EGAF00006623692 fastq.gz 314.5 MB
EGAF00006623693 fastq.gz 223.5 MB
EGAF00006623694 fastq.gz 308.4 MB
EGAF00006623695 fastq.gz 225.1 MB
EGAF00006623696 fastq.gz 320.4 MB
EGAF00006623697 fastq.gz 248.2 MB
EGAF00006623698 fastq.gz 352.7 MB
EGAF00006623699 fastq.gz 358.2 MB
EGAF00006623700 fastq.gz 503.6 MB
EGAF00006623701 fastq.gz 217.5 MB
EGAF00006623702 fastq.gz 304.9 MB
EGAF00006623703 fastq.gz 209.8 MB
EGAF00006623704 fastq.gz 296.6 MB
EGAF00006623705 fastq.gz 246.0 MB
EGAF00006623706 fastq.gz 354.5 MB
EGAF00006623707 fastq.gz 227.0 MB
EGAF00006623708 fastq.gz 319.2 MB
EGAF00006623709 fastq.gz 179.2 MB
EGAF00006623710 fastq.gz 253.4 MB
EGAF00006623711 fastq.gz 196.0 MB
EGAF00006623712 fastq.gz 272.1 MB
EGAF00006623713 fastq.gz 174.3 MB
EGAF00006623714 fastq.gz 251.7 MB
EGAF00006623715 fastq.gz 342.5 MB
EGAF00006623716 fastq.gz 498.0 MB
EGAF00006623717 fastq.gz 177.7 MB
EGAF00006623718 fastq.gz 256.9 MB
EGAF00006623719 fastq.gz 203.3 MB
EGAF00006623720 fastq.gz 283.2 MB
EGAF00006623721 fastq.gz 177.7 MB
EGAF00006623722 fastq.gz 251.8 MB
EGAF00006623723 fastq.gz 251.7 MB
EGAF00006623724 fastq.gz 356.2 MB
EGAF00006623725 fastq.gz 204.9 MB
EGAF00006623726 fastq.gz 293.9 MB
EGAF00006623727 fastq.gz 167.5 MB
EGAF00006623728 fastq.gz 242.0 MB
EGAF00006623729 fastq.gz 249.0 MB
EGAF00006623730 fastq.gz 360.4 MB
EGAF00006623731 fastq.gz 280.7 MB
EGAF00006623732 fastq.gz 409.4 MB
EGAF00006623733 fastq.gz 200.0 MB
EGAF00006623734 fastq.gz 288.2 MB
EGAF00006623735 fastq.gz 259.9 MB
EGAF00006623736 fastq.gz 379.4 MB
EGAF00006623737 fastq.gz 269.6 MB
EGAF00006623738 fastq.gz 382.8 MB
EGAF00006623739 fastq.gz 256.9 MB
EGAF00006623740 fastq.gz 362.3 MB
EGAF00006623741 fastq.gz 199.2 MB
EGAF00006623742 fastq.gz 284.8 MB
EGAF00006623743 fastq.gz 253.0 MB
EGAF00006623744 fastq.gz 358.2 MB
EGAF00006623745 fastq.gz 205.8 MB
EGAF00006623746 fastq.gz 289.0 MB
EGAF00006623747 fastq.gz 276.2 MB
EGAF00006623748 fastq.gz 393.3 MB
EGAF00006623749 fastq.gz 231.0 MB
EGAF00006623750 fastq.gz 337.5 MB
EGAF00006623751 fastq.gz 225.8 MB
EGAF00006623752 fastq.gz 316.0 MB
EGAF00006623753 fastq.gz 186.6 MB
EGAF00006623754 fastq.gz 263.5 MB
EGAF00006623755 fastq.gz 176.4 MB
EGAF00006623756 fastq.gz 250.9 MB
253 Files (76.6 GB)