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IL1R1+ cancer-associated fibroblasts drive tumor development and immunosuppression in colorectal cancer

180502: RNA-Sequencing data of cocultured matched CRC patient (P4) derived normal fibroblasts (NFs), cancer associated fibroblasts (CAFs) and tumor spheroids. 200503_coculture: RNA-Sequencing data of cocultured CRC patient derived normal fibroblasts (NFs) or cancer associated fibroblasts (CAFs) (P16, P19, P22, P32, P41, P42) and tumor spheroids (HT29). 200503_il1b: RNA-Sequencing data of IL-1β stimulated fibroblasts (NFs and CAFs) Cole: scRNA-sequencing of matched CRC tumour samples and normal tissue counterparts derived from 3 patients. 220501: RNA-Sequencing of FACS sorted IL1R1 high and IL1R1 low CT5.3 CAFs

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Data Access Policy of the University of Luxembourg for sensitive genomic data

Data Access Policy 1. The access to the data will be granted by the Data Access Committee (DAC). The DACs will review and approve or disapprove all requests from the research community for data access. Decisions to grant access are made based on whether the request conforms to the specifications within this data access policy. If the DAC decides to grant access, a Data Access Agreement must be signed between the data owner and the user institution. 2. Applications are welcome for studies in all research areas 3. The User Institution agrees to only use these Data for the purpose of the Project and only for Research Purposes. 4. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. 5. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 6. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 7. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 8. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 9. The User Institution agrees to follow the Publication Policy which includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 10. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of of these Data, or conclusion drawn directly from these Data 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001007205 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00008051729 fastq.gz 1.8 GB
EGAF00008051730 fastq.gz 1.8 GB
EGAF00008051731 fastq.gz 1.9 GB
EGAF00008051732 fastq.gz 1.6 GB
EGAF00008051733 fastq.gz 2.0 GB
EGAF00008051734 fastq.gz 1.8 GB
EGAF00008051735 fastq.gz 1.6 GB
EGAF00008051736 fastq.gz 1.8 GB
EGAF00008051737 fastq.gz 1.8 GB
EGAF00008051738 fastq.gz 1.7 GB
EGAF00008051739 fastq.gz 1.7 GB
EGAF00008051740 fastq.gz 1.5 GB
EGAF00008051741 fastq.gz 1.5 GB
EGAF00008051742 fastq.gz 1.6 GB
EGAF00008051743 fastq.gz 1.5 GB
EGAF00008051744 fastq.gz 1.9 GB
EGAF00008051745 fastq.gz 2.0 GB
EGAF00008051746 fastq.gz 1.8 GB
EGAF00008051747 fastq.gz 1.8 GB
EGAF00008051748 fastq.gz 3.5 GB
EGAF00008051749 fastq.gz 1.5 GB
EGAF00008051750 fastq.gz 1.0 GB
EGAF00008051751 fastq.gz 1.5 GB
EGAF00008051752 fastq.gz 1.8 GB
EGAF00008051753 fastq.gz 1.7 GB
EGAF00008051754 fastq.gz 1.8 GB
EGAF00008051755 fastq.gz 1.9 GB
EGAF00008051756 fastq.gz 1.5 GB
EGAF00008051757 fastq.gz 1.7 GB
EGAF00008051758 fastq.gz 1.9 GB
EGAF00008051759 fastq.gz 1.9 GB
EGAF00008051760 fastq.gz 1.7 GB
EGAF00008051761 fastq.gz 1.9 GB
EGAF00008051762 fastq.gz 1.9 GB
EGAF00008051763 fastq.gz 1.6 GB
EGAF00008051764 fastq.gz 1.3 GB
EGAF00008051765 fastq.gz 1.4 GB
EGAF00008051766 fastq.gz 1.2 GB
EGAF00008051767 fastq.gz 2.0 GB
EGAF00008051768 fastq.gz 2.0 GB
EGAF00008051769 fastq.gz 1.7 GB
EGAF00008051770 fastq.gz 1.7 GB
EGAF00008051771 fastq.gz 1.7 GB
EGAF00008051772 fastq.gz 1.8 GB
EGAF00008051773 fastq.gz 1.8 GB
EGAF00008051774 fastq.gz 1.4 GB
EGAF00008051775 fastq.gz 1.5 GB
EGAF00008051776 fastq.gz 1.5 GB
EGAF00008051777 fastq.gz 1.5 GB
EGAF00008051778 fastq.gz 1.8 GB
EGAF00008051779 fastq.gz 1.6 GB
EGAF00008051780 fastq.gz 1.7 GB
EGAF00008051781 fastq.gz 1.9 GB
EGAF00008051782 fastq.gz 1.5 GB
EGAF00008051783 fastq.gz 1.9 GB
EGAF00008051784 fastq.gz 1.4 GB
EGAF00008051785 fastq.gz 1.5 GB
EGAF00008051786 fastq.gz 1.4 GB
EGAF00008051787 fastq.gz 1.4 GB
EGAF00008051788 fastq.gz 1.5 GB
EGAF00008051789 fastq.gz 1.6 GB
EGAF00008051790 fastq.gz 1.6 GB
EGAF00008051791 fastq.gz 1.3 GB
EGAF00008051792 fastq.gz 1.6 GB
EGAF00008051793 fastq.gz 1.8 GB
EGAF00008051794 bam 8.7 GB
EGAF00008051795 bam 9.1 GB
EGAF00008051796 bam 9.0 GB
EGAF00008051797 bam 9.0 GB
EGAF00008051798 bam 8.3 GB
EGAF00008051799 bam 9.1 GB
EGAF00008051800 fastq.gz 1.7 GB
EGAF00008051801 fastq.gz 1.4 GB
EGAF00008051802 fastq.gz 925.2 MB
EGAF00008051803 fastq.gz 930.6 MB
EGAF00008051804 fastq.gz 886.7 MB
EGAF00008051805 fastq.gz 891.2 MB
EGAF00008051806 fastq.gz 935.2 MB
EGAF00008051807 fastq.gz 941.6 MB
EGAF00008051808 fastq.gz 945.0 MB
EGAF00008051809 fastq.gz 948.5 MB
EGAF00008051810 fastq.gz 911.2 MB
EGAF00008051811 fastq.gz 918.2 MB
EGAF00008051812 fastq.gz 938.9 MB
EGAF00008051813 fastq.gz 942.7 MB
EGAF00008051814 fastq.gz 1.5 GB
EGAF00008051815 fastq.gz 1.7 GB
EGAF00008051816 fastq.gz 1.7 GB
EGAF00008051817 fastq.gz 1.7 GB
EGAF00008051818 fastq.gz 1.7 GB
EGAF00008051819 fastq.gz 1.4 GB
EGAF00008051820 fastq.gz 1.8 GB
EGAF00008051821 fastq.gz 1.7 GB
EGAF00008051822 fastq.gz 1.2 GB
EGAF00008051823 fastq.gz 1.4 GB
EGAF00008051824 fastq.gz 1.5 GB
EGAF00008051825 fastq.gz 1.6 GB
EGAF00008051826 fastq.gz 1.7 GB
EGAF00008051827 fastq.gz 1.6 GB
EGAF00008051828 fastq.gz 1.3 GB
EGAF00008051829 fastq.gz 1.3 GB
EGAF00008051830 fastq.gz 1.7 GB
EGAF00008051831 fastq.gz 1.7 GB
103 Files (205.7 GB)