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Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole genome sequencing with histopathological features

We performed whole genome sequencing on 42 prostate cancer samples from the prostate, seminal vesicles and regional lymph nodes of five treatment-naive patients with locally advanced disease who underwent radical prostatectomy. Whole genome sequencing was performed as 150bp paired end reads on the Illumina NovaSeq 6000 platform.

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Data access policy for ProMOTE Genomics project

Investigators who download restricted data from this dataset should: - Not attempt to identify individual human research participants from whom the data were obtained. - Acknowledge in all oral or written presentations, disclosures, or publications the specific dataset(s) or applicable accession number(s)and the repositories through which the investigator accessed any data. Any user requesting access to this data must apply for authorization, which is granted by the ProMOTE Data Access Committee (DAC). The DAC will review and approve or disapprove all requests from the research community for data access. Decisions to grant access are made based on whether the request conforms to the specifications of the Research Ethics Committee approval and program specific requirements or procedures (if any).

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001007438 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00008172687 cram 75.4 GB
EGAF00008172688 cram 77.2 GB
EGAF00008172689 cram 65.5 GB
EGAF00008172690 cram 59.5 GB
EGAF00008172691 cram 53.1 GB
EGAF00008172692 cram 49.7 GB
EGAF00008172693 cram 60.3 GB
EGAF00008172694 cram 48.3 GB
EGAF00008172695 cram 42.4 GB
EGAF00008172696 cram 42.5 GB
EGAF00008172697 cram 26.3 GB
EGAF00008172698 cram 44.8 GB
EGAF00008172699 cram 40.6 GB
EGAF00008172700 cram 46.9 GB
EGAF00008172701 cram 19.7 GB
EGAF00008172702 cram 14.5 GB
EGAF00008172703 cram 47.6 GB
EGAF00008172704 cram 47.0 GB
EGAF00008172705 cram 40.0 GB
EGAF00008172706 cram 43.4 GB
EGAF00008172707 cram 48.1 GB
EGAF00008172708 cram 27.8 GB
EGAF00008172709 cram 101.2 GB
EGAF00008172710 cram 42.3 GB
EGAF00008172711 cram 40.2 GB
EGAF00008172712 cram 51.7 GB
EGAF00008172713 cram 44.8 GB
EGAF00008172714 cram 46.9 GB
EGAF00008172715 cram 46.9 GB
EGAF00008172716 cram 51.0 GB
EGAF00008172717 cram 13.8 GB
EGAF00008172718 cram 75.9 GB
EGAF00008172719 cram 42.7 GB
EGAF00008172720 cram 23.6 GB
EGAF00008172721 cram 48.4 GB
EGAF00008172722 cram 52.0 GB
EGAF00008172723 cram 40.3 GB
EGAF00008172724 cram 41.8 GB
EGAF00008172725 cram 45.1 GB
EGAF00008172726 cram 42.8 GB
EGAF00008172727 cram 46.4 GB
EGAF00008172728 cram 47.3 GB
EGAF00008172729 cram 45.5 GB
EGAF00008172730 cram 45.1 GB
EGAF00008172731 cram 44.3 GB
EGAF00008172732 cram 47.4 GB
EGAF00008172733 cram 42.6 GB
EGAF00008172734 cram 52.1 GB
48 Files (2.2 TB)