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Human Spermatogenesis Methylome

The dataset contains the methylome EM-sequencing raw data (fastq) of different spermatogenic cells from 5 human males (three controls and two crypotzoospermic). The datasets correspond to the following cell types: undifferentiated spermatogonia, differentiating spermatogonia, 4C spermatocytes, and 1C spermatids (this cell type only for the control individuals)

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MGC-DAG Version 1 - 18.3.22

Data Access Agreement These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom CeRA grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: CeRA and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify CeRA within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify CeRA prior to any significant changes to the protocol for the Project. 14. The User Institution will notify CeRA as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. CeRA may terminate this agreement at any moment by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than CeRA. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of the Federal Republic of Germany and the State of North Rhine-Westphalia and shall be subject to the exclusive jurisdiction of their courts.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001007449 Epigenetics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00008176882 fastq.gz 1.7 GB
EGAF00008176883 fastq.gz 1.7 GB
EGAF00008176884 fastq.gz 1.6 GB
EGAF00008176885 fastq.gz 1.7 GB
EGAF00008176886 fastq.gz 1.7 GB
EGAF00008176887 fastq.gz 1.7 GB
EGAF00008176888 fastq.gz 1.7 GB
EGAF00008176889 fastq.gz 1.7 GB
EGAF00008176890 fastq.gz 1.7 GB
EGAF00008176891 fastq.gz 1.7 GB
EGAF00008176892 fastq.gz 1.6 GB
EGAF00008176893 fastq.gz 1.7 GB
EGAF00008176894 fastq.gz 1.7 GB
EGAF00008176895 fastq.gz 1.7 GB
EGAF00008176896 fastq.gz 1.7 GB
EGAF00008176897 fastq.gz 1.7 GB
EGAF00008176898 fastq.gz 1.6 GB
EGAF00008176899 fastq.gz 1.6 GB
EGAF00008176900 fastq.gz 1.5 GB
EGAF00008176901 fastq.gz 1.6 GB
EGAF00008176902 fastq.gz 1.6 GB
EGAF00008176903 fastq.gz 1.6 GB
EGAF00008176904 fastq.gz 1.5 GB
EGAF00008176905 fastq.gz 1.6 GB
EGAF00008176906 fastq.gz 1.7 GB
EGAF00008176907 fastq.gz 1.7 GB
EGAF00008176908 fastq.gz 1.6 GB
EGAF00008176909 fastq.gz 1.7 GB
EGAF00008176910 fastq.gz 1.7 GB
EGAF00008176911 fastq.gz 1.7 GB
EGAF00008176912 fastq.gz 1.7 GB
EGAF00008176913 fastq.gz 1.7 GB
EGAF00008176914 fastq.gz 1.6 GB
EGAF00008176915 fastq.gz 1.6 GB
EGAF00008176916 fastq.gz 1.5 GB
EGAF00008176917 fastq.gz 1.5 GB
EGAF00008176918 fastq.gz 1.5 GB
EGAF00008176919 fastq.gz 1.6 GB
EGAF00008176920 fastq.gz 1.5 GB
EGAF00008176921 fastq.gz 1.6 GB
EGAF00008176922 fastq.gz 1.7 GB
EGAF00008176923 fastq.gz 1.7 GB
EGAF00008176924 fastq.gz 1.6 GB
EGAF00008176925 fastq.gz 1.7 GB
EGAF00008176926 fastq.gz 1.7 GB
EGAF00008176927 fastq.gz 1.7 GB
EGAF00008176928 fastq.gz 1.7 GB
EGAF00008176929 fastq.gz 1.7 GB
EGAF00008176930 fastq.gz 1.9 GB
EGAF00008176931 fastq.gz 1.9 GB
EGAF00008176932 fastq.gz 1.8 GB
EGAF00008176933 fastq.gz 1.8 GB
EGAF00008176934 fastq.gz 1.8 GB
EGAF00008176935 fastq.gz 1.9 GB
EGAF00008176936 fastq.gz 1.8 GB
EGAF00008176937 fastq.gz 1.9 GB
EGAF00008176938 fastq.gz 1.5 GB
EGAF00008176939 fastq.gz 1.5 GB
EGAF00008176940 fastq.gz 1.5 GB
EGAF00008176941 fastq.gz 1.5 GB
EGAF00008176942 fastq.gz 1.5 GB
EGAF00008176943 fastq.gz 1.5 GB
EGAF00008176944 fastq.gz 1.5 GB
EGAF00008176945 fastq.gz 1.5 GB
EGAF00008176946 fastq.gz 1.7 GB
EGAF00008176947 fastq.gz 1.8 GB
EGAF00008176948 fastq.gz 1.7 GB
EGAF00008176949 fastq.gz 1.7 GB
EGAF00008176950 fastq.gz 1.7 GB
EGAF00008176951 fastq.gz 1.7 GB
EGAF00008176952 fastq.gz 1.7 GB
EGAF00008176953 fastq.gz 1.7 GB
EGAF00008176954 fastq.gz 1.7 GB
EGAF00008176955 fastq.gz 1.8 GB
EGAF00008176956 fastq.gz 1.7 GB
EGAF00008176957 fastq.gz 1.7 GB
EGAF00008176958 fastq.gz 1.7 GB
EGAF00008176959 fastq.gz 1.7 GB
EGAF00008176960 fastq.gz 1.7 GB
EGAF00008176961 fastq.gz 1.7 GB
EGAF00008176962 fastq.gz 1.3 GB
EGAF00008176963 fastq.gz 1.3 GB
EGAF00008176964 fastq.gz 1.2 GB
EGAF00008176965 fastq.gz 1.3 GB
EGAF00008176966 fastq.gz 1.3 GB
EGAF00008176967 fastq.gz 1.3 GB
EGAF00008176968 fastq.gz 1.3 GB
EGAF00008176969 fastq.gz 1.3 GB
EGAF00008176970 fastq.gz 1.7 GB
EGAF00008176971 fastq.gz 1.7 GB
EGAF00008176972 fastq.gz 1.6 GB
EGAF00008176973 fastq.gz 1.7 GB
EGAF00008176974 fastq.gz 1.7 GB
EGAF00008176975 fastq.gz 1.7 GB
EGAF00008176976 fastq.gz 1.7 GB
EGAF00008176977 fastq.gz 1.7 GB
EGAF00008176978 fastq.gz 6.8 GB
EGAF00008176979 fastq.gz 6.8 GB
EGAF00008176980 fastq.gz 6.7 GB
EGAF00008176981 fastq.gz 6.7 GB
EGAF00008176982 fastq.gz 6.9 GB
EGAF00008176983 fastq.gz 6.8 GB
EGAF00008176984 fastq.gz 6.9 GB
EGAF00008176985 fastq.gz 6.8 GB
EGAF00008176986 fastq.gz 6.5 GB
EGAF00008176987 fastq.gz 6.5 GB
EGAF00008176988 fastq.gz 6.5 GB
EGAF00008176989 fastq.gz 6.5 GB
EGAF00008176990 fastq.gz 7.0 GB
EGAF00008176991 fastq.gz 7.1 GB
EGAF00008176992 fastq.gz 7.0 GB
EGAF00008176993 fastq.gz 7.1 GB
EGAF00008176994 fastq.gz 6.5 GB
EGAF00008176995 fastq.gz 6.6 GB
EGAF00008176996 fastq.gz 6.5 GB
EGAF00008176997 fastq.gz 6.5 GB
EGAF00008176998 fastq.gz 7.0 GB
EGAF00008176999 fastq.gz 7.0 GB
EGAF00008177000 fastq.gz 7.0 GB
EGAF00008177001 fastq.gz 7.0 GB
EGAF00008177002 fastq.gz 7.7 GB
EGAF00008177003 fastq.gz 7.7 GB
EGAF00008177004 fastq.gz 7.7 GB
EGAF00008177005 fastq.gz 7.7 GB
EGAF00008177006 fastq.gz 6.4 GB
EGAF00008177007 fastq.gz 6.4 GB
EGAF00008177008 fastq.gz 6.4 GB
EGAF00008177009 fastq.gz 6.4 GB
EGAF00008177010 fastq.gz 7.1 GB
EGAF00008177011 fastq.gz 7.1 GB
EGAF00008177012 fastq.gz 7.1 GB
EGAF00008177013 fastq.gz 7.1 GB
EGAF00008177014 fastq.gz 7.1 GB
EGAF00008177015 fastq.gz 7.0 GB
EGAF00008177016 fastq.gz 7.1 GB
EGAF00008177017 fastq.gz 7.0 GB
EGAF00008177018 fastq.gz 5.0 GB
EGAF00008177019 fastq.gz 5.1 GB
EGAF00008177020 fastq.gz 5.0 GB
EGAF00008177021 fastq.gz 5.0 GB
EGAF00008177022 fastq.gz 6.9 GB
EGAF00008177023 fastq.gz 7.0 GB
EGAF00008177024 fastq.gz 6.9 GB
EGAF00008177025 fastq.gz 7.0 GB
EGAF00008177026 fastq.gz 1.4 GB
EGAF00008177027 fastq.gz 1.4 GB
EGAF00008177028 fastq.gz 1.3 GB
EGAF00008177029 fastq.gz 1.4 GB
EGAF00008177030 fastq.gz 1.4 GB
EGAF00008177031 fastq.gz 1.4 GB
EGAF00008177032 fastq.gz 1.4 GB
EGAF00008177033 fastq.gz 1.4 GB
EGAF00008177034 fastq.gz 14.0 GB
EGAF00008177035 fastq.gz 14.5 GB
EGAF00008177036 fastq.gz 16.4 GB
EGAF00008177037 fastq.gz 17.2 GB
EGAF00008177038 fastq.gz 20.8 GB
EGAF00008177039 fastq.gz 21.5 GB
EGAF00008177040 fastq.gz 16.5 GB
EGAF00008177041 fastq.gz 17.4 GB
EGAF00008177042 fastq.gz 13.7 GB
EGAF00008177043 fastq.gz 14.2 GB
EGAF00008177044 fastq.gz 16.6 GB
EGAF00008177045 fastq.gz 17.5 GB
EGAF00008177046 fastq.gz 14.4 GB
EGAF00008177047 fastq.gz 15.2 GB
EGAF00008177048 fastq.gz 13.1 GB
EGAF00008177049 fastq.gz 13.8 GB
EGAF00008177050 fastq.gz 18.0 GB
EGAF00008177051 fastq.gz 19.0 GB
EGAF00008177052 fastq.gz 5.2 GB
EGAF00008177053 fastq.gz 5.3 GB
EGAF00008177054 fastq.gz 3.1 GB
EGAF00008177055 fastq.gz 3.2 GB
EGAF00008177056 fastq.gz 3.2 GB
EGAF00008177057 fastq.gz 3.3 GB
EGAF00008177058 fastq.gz 6.1 GB
EGAF00008177059 fastq.gz 6.3 GB
EGAF00008177060 fastq.gz 2.8 GB
EGAF00008177061 fastq.gz 3.0 GB
EGAF00008177062 fastq.gz 5.2 GB
EGAF00008177063 fastq.gz 5.5 GB
EGAF00008177064 fastq.gz 6.6 GB
EGAF00008177065 fastq.gz 7.0 GB
184 Files (851.1 GB)