Phase II Trial with Correlative Genomic Analysis of Durvalumab plus Pazopanib Combination in Patients with Advanced Soft Tissue Sarcomas
This study includes an open-label, phase 2 study to determine the activity of the anti-VEGF receptor tyrosine-kinase inhibitor, pazopanib, combined with the anti-PD-L1 immune checkpoint inhibitor, durvalumab, in unselected advanced sarcomas. We conducted whole exome and transcriptomic sequencing with pre-treatment tissue biopsy to correlate clinical outcomes with molecular and genomic biomarkers to identify patients who would most likely benefit from the combination treatment.
- 05/01/2024
- 83 samples
- DAC: EGAC50000000046
- Technology: Illumina HiSeq 2500
Data policy
We generally respect the guidelines of NIH genomic data sharing policy, but can be overriden by consensual decision of DAC in exceptional cases.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS50000000082 | Cancer Genomics |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF50000057154 | fq.gz | 3.3 GB | ||
| EGAF50000057155 | fq.gz | 3.4 GB | ||
| EGAF50000057156 | fq.gz | 2.6 GB | ||
| EGAF50000057157 | fq.gz | 2.8 GB | ||
| EGAF50000057158 | fq.gz | 2.5 GB | ||
| EGAF50000057159 | fq.gz | 2.6 GB | ||
| EGAF50000057160 | fq.gz | 2.5 GB | ||
| EGAF50000057161 | fq.gz | 2.7 GB | ||
| EGAF50000057162 | fq.gz | 2.4 GB | ||
| EGAF50000057163 | fq.gz | 2.6 GB | ||
| EGAF50000057164 | fq.gz | 2.3 GB | ||
| EGAF50000057165 | fq.gz | 2.3 GB | ||
| EGAF50000057166 | fq.gz | 2.7 GB | ||
| EGAF50000057167 | fq.gz | 2.8 GB | ||
| EGAF50000057168 | fq.gz | 2.8 GB | ||
| EGAF50000057169 | fq.gz | 3.0 GB | ||
| EGAF50000057170 | fq.gz | 2.4 GB | ||
| EGAF50000057171 | fq.gz | 2.6 GB | ||
| EGAF50000057172 | fq.gz | 2.5 GB | ||
| EGAF50000057173 | fq.gz | 2.6 GB | ||
| EGAF50000057174 | fq.gz | 6.4 GB | ||
| EGAF50000057175 | fq.gz | 6.0 GB | ||
| EGAF50000057176 | fq.gz | 3.0 GB | ||
| EGAF50000057177 | fq.gz | 3.1 GB | ||
| EGAF50000057178 | fq.gz | 2.5 GB | ||
| EGAF50000057179 | fq.gz | 2.6 GB | ||
| EGAF50000057180 | fq.gz | 4.7 GB | ||
| EGAF50000057181 | fq.gz | 4.5 GB | ||
| EGAF50000057182 | fq.gz | 5.3 GB | ||
| EGAF50000057183 | fq.gz | 5.6 GB | ||
| EGAF50000057184 | fq.gz | 5.8 GB | ||
| EGAF50000057185 | fq.gz | 6.2 GB | ||
| EGAF50000057186 | fq.gz | 6.9 GB | ||
| EGAF50000057187 | fq.gz | 7.2 GB | ||
| EGAF50000057188 | fq.gz | 2.5 GB | ||
| EGAF50000057189 | fq.gz | 2.7 GB | ||
| EGAF50000057190 | fq.gz | 4.8 GB | ||
| EGAF50000057191 | fq.gz | 5.3 GB | ||
| EGAF50000057192 | fq.gz | 44.8 MB | ||
| EGAF50000057193 | fq.gz | 2.2 GB | ||
| EGAF50000057194 | fq.gz | 6.4 GB | ||
| EGAF50000057195 | fq.gz | 6.7 GB | ||
| EGAF50000057196 | fq.gz | 6.0 GB | ||
| EGAF50000057197 | fq.gz | 6.3 GB | ||
| EGAF50000057198 | fq.gz | 6.1 GB | ||
| EGAF50000057199 | fq.gz | 6.5 GB | ||
| EGAF50000057200 | fq.gz | 3.3 GB | ||
| EGAF50000057201 | fq.gz | 3.5 GB | ||
| EGAF50000057202 | fq.gz | 5.4 GB | ||
| EGAF50000057203 | fq.gz | 5.5 GB | ||
| EGAF50000057204 | fq.gz | 2.6 GB | ||
| EGAF50000057205 | fq.gz | 2.7 GB | ||
| EGAF50000057206 | fq.gz | 5.7 GB | ||
| EGAF50000057207 | fq.gz | 6.0 GB | ||
| EGAF50000057208 | fq.gz | 4.9 GB | ||
| EGAF50000057209 | fq.gz | 5.8 GB | ||
| EGAF50000057210 | fq.gz | 4.7 GB | ||
| EGAF50000057211 | fq.gz | 5.1 GB | ||
| EGAF50000057212 | fq.gz | 4.4 GB | ||
| EGAF50000057213 | fq.gz | 4.7 GB | ||
| EGAF50000057214 | fq.gz | 4.9 GB | ||
| EGAF50000057215 | fq.gz | 5.2 GB | ||
| EGAF50000057216 | fq.gz | 5.2 GB | ||
| EGAF50000057217 | fq.gz | 5.5 GB | ||
| EGAF50000057218 | fq.gz | 4.4 GB | ||
| EGAF50000057219 | fq.gz | 4.6 GB | ||
| EGAF50000057220 | fq.gz | 5.8 GB | ||
| EGAF50000057221 | fq.gz | 6.0 GB | ||
| EGAF50000057222 | fq.gz | 4.8 GB | ||
| EGAF50000057223 | fq.gz | 5.0 GB | ||
| EGAF50000057224 | fq.gz | 5.4 GB | ||
| EGAF50000057225 | fq.gz | 5.8 GB | ||
| EGAF50000057226 | fq.gz | 7.1 GB | ||
| EGAF50000057227 | fq.gz | 7.4 GB | ||
| EGAF50000057228 | fq.gz | 5.4 GB | ||
| EGAF50000057229 | fq.gz | 5.8 GB | ||
| EGAF50000057230 | fq.gz | 5.3 GB | ||
| EGAF50000057231 | fq.gz | 5.6 GB | ||
| EGAF50000057232 | fq.gz | 6.3 GB | ||
| EGAF50000057233 | fq.gz | 6.5 GB | ||
| EGAF50000057234 | fq.gz | 5.3 GB | ||
| EGAF50000057235 | fq.gz | 5.6 GB | ||
| EGAF50000057236 | fq.gz | 5.2 GB | ||
| EGAF50000057237 | fq.gz | 5.8 GB | ||
| EGAF50000057238 | fq.gz | 5.0 GB | ||
| EGAF50000057239 | fq.gz | 5.3 GB | ||
| EGAF50000057240 | fq.gz | 5.2 GB | ||
| EGAF50000057241 | fq.gz | 5.5 GB | ||
| EGAF50000057242 | fq.gz | 0 Bytes | ||
| EGAF50000057243 | fq.gz | 5.6 GB | ||
| EGAF50000057244 | fq.gz | 6.5 GB | ||
| EGAF50000057245 | fq.gz | 6.2 GB | ||
| EGAF50000057246 | fq.gz | 4.9 GB | ||
| EGAF50000057247 | fq.gz | 5.3 GB | ||
| EGAF50000057248 | fq.gz | 4.6 GB | ||
| EGAF50000057249 | fq.gz | 5.0 GB | ||
| EGAF50000057250 | fq.gz | 5.7 GB | ||
| EGAF50000057251 | fq.gz | 6.0 GB | ||
| EGAF50000057252 | fq.gz | 6.1 GB | ||
| EGAF50000057253 | fq.gz | 6.5 GB | ||
| EGAF50000057254 | fq.gz | 5.8 GB | ||
| EGAF50000057255 | fq.gz | 6.1 GB | ||
| EGAF50000057256 | fq.gz | 6.1 GB | ||
| EGAF50000057257 | fq.gz | 6.5 GB | ||
| EGAF50000057258 | fq.gz | 5.2 GB | ||
| EGAF50000057259 | fq.gz | 5.5 GB | ||
| EGAF50000057260 | fq.gz | 5.5 GB | ||
| EGAF50000057261 | fq.gz | 5.7 GB | ||
| EGAF50000057262 | fq.gz | 2.4 GB | ||
| EGAF50000057263 | fq.gz | 516.8 MB | ||
| EGAF50000057264 | fq.gz | 3.2 GB | ||
| EGAF50000057265 | fq.gz | 3.4 GB | ||
| EGAF50000057266 | fq.gz | 3.4 GB | ||
| EGAF50000057267 | fq.gz | 3.6 GB | ||
| EGAF50000057268 | fq.gz | 3.0 GB | ||
| EGAF50000057269 | fq.gz | 2.9 GB | ||
| EGAF50000057270 | fq.gz | 2.9 GB | ||
| EGAF50000057271 | fq.gz | 3.1 GB | ||
| EGAF50000057272 | fq.gz | 2.9 GB | ||
| EGAF50000057273 | fq.gz | 3.0 GB | ||
| EGAF50000057274 | fq.gz | 2.6 GB | ||
| EGAF50000057275 | fq.gz | 2.7 GB | ||
| EGAF50000057276 | fq.gz | 2.7 GB | ||
| EGAF50000057277 | fq.gz | 2.9 GB | ||
| EGAF50000057278 | fq.gz | 3.5 GB | ||
| EGAF50000057279 | fq.gz | 3.7 GB | ||
| EGAF50000057280 | fq.gz | 2.7 GB | ||
| EGAF50000057281 | fq.gz | 2.9 GB | ||
| EGAF50000057282 | fq.gz | 2.9 GB | ||
| EGAF50000057283 | fq.gz | 3.1 GB | ||
| EGAF50000057284 | fq.gz | 2.6 GB | ||
| EGAF50000057285 | fq.gz | 2.8 GB | ||
| EGAF50000057286 | fq.gz | 2.6 GB | ||
| EGAF50000057287 | fq.gz | 2.7 GB | ||
| EGAF50000057288 | fq.gz | 2.9 GB | ||
| EGAF50000057289 | fq.gz | 3.0 GB | ||
| EGAF50000057290 | fq.gz | 2.8 GB | ||
| EGAF50000057291 | fq.gz | 3.0 GB | ||
| EGAF50000057292 | fq.gz | 3.0 GB | ||
| EGAF50000057293 | fq.gz | 3.1 GB | ||
| EGAF50000057294 | fq.gz | 3.7 GB | ||
| EGAF50000057295 | fq.gz | 3.9 GB | ||
| EGAF50000057296 | fq.gz | 2.9 GB | ||
| EGAF50000057297 | fq.gz | 3.1 GB | ||
| EGAF50000057298 | fq.gz | 3.2 GB | ||
| EGAF50000057299 | fq.gz | 3.4 GB | ||
| EGAF50000057300 | fq.gz | 2.9 GB | ||
| EGAF50000057301 | fq.gz | 3.1 GB | ||
| EGAF50000057302 | fq.gz | 5.4 GB | ||
| EGAF50000057303 | fq.gz | 5.1 GB | ||
| EGAF50000057304 | fq.gz | 5.7 GB | ||
| EGAF50000057305 | fq.gz | 6.0 GB | ||
| EGAF50000057306 | fq.gz | 4.7 GB | ||
| EGAF50000057307 | fq.gz | 5.4 GB | ||
| EGAF50000057308 | fq.gz | 5.1 GB | ||
| EGAF50000057309 | fq.gz | 5.5 GB | ||
| EGAF50000057310 | fq.gz | 5.1 GB | ||
| EGAF50000057311 | fq.gz | 5.4 GB | ||
| EGAF50000057312 | fq.gz | 4.6 GB | ||
| EGAF50000057313 | fq.gz | 4.9 GB | ||
| EGAF50000057314 | fq.gz | 5.3 GB | ||
| EGAF50000057315 | fq.gz | 5.8 GB | ||
| EGAF50000057316 | fq.gz | 5.8 GB | ||
| EGAF50000057317 | fq.gz | 6.2 GB | ||
| EGAF50000057318 | fq.gz | 4.7 GB | ||
| EGAF50000057319 | fq.gz | 5.1 GB | ||
| 166 Files (721.8 GB) | ||||