Phylogenetic analysis of combined lobular and ductal carcinoma of the breast

Breast cancer manifests in diverse forms, with particular reference to various cell types harboring different mutations and gene expression profiles. To elucidate the clonal relationship between cancer cells in tumors composed of both ductal and lobular phenotypes, we analyzed two combined lobular and ductal carcinoma (CLDC) cases, including one mixed ductal-lobular carcinoma (MDL) lesion, by next generation sequencing.

• Type: Tumor vs. Matched-Normal
• Archiver: Japanese Genotype-phenotype Archive (JGA)